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Re-inventing Drug Development
The biopharmaceutical industry has entered an era of unprecedented change and challenge, characterized by increasing pricing pressures, rising rates of attrition in the product development lifecycle, and decreasing scientific innovation. The most successful products are losing patent protection, and pipelines have been unable to fill the gap. This
Re-inventing Drug Development
The biopharmaceutical industry has entered an era of unprecedented change and challenge, characterized by increasing pricing pressures, rising rates of attrition in the product development lifecycle, and decreasing scientific innovation. The most successful products are losing patent protection, and pipelines have been unable to fill the gap. This book explores the evolving definition of innovation in therapeutic product development and begins to examine its effects on the life sciences R&D industry. Historically, scientific innovation alone was sufficient to maintain ROI and deliver on unmet medical needs. However, with many forces now conspiring to increase pressures on the commoditization...
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Probability and Statistics for Economists
A comprehensive and up-to-date introduction to the mathematics that all economics students need to know Probability theory is the quantitative language used to handle uncertainty and is the foundation of modern statistics. Probability and Statistics for Economists provides graduate and PhD students with an essential introduction to mathematical probability and statistical theory, which are the basis of the methods used in econometrics. This incisive textbook teaches fundamental concepts, emphasizes modern, real-world applications, and gives students an intuitive understanding of the mathematics that every economist needs to know. Covers probability and statistics with mathematical rigor whil...
Drug Safety Data
Drug Safety Data: How to Analyze, Summarize and Interpret to Determine Risk was selected for The First Clinical Research Bookshelf - Essential reading for clinical research professionals by the Journal of Clinical Research Best Practices. Drug Safety Data: How to Analyze, Summarize and Interpret to Determine Risk provides drug safety/pharmacovogilance professionals, pharmaceutical and clinical research scientists, statisticians, programmers, medical writers, and technicians with an accessible, practical framework for the analysis, summary and interpretation of drug safety data. The only guide of its kind, Drug Safety Data: How to Analyze, Summarize and Interpret to Determine Risk is an inval...
Systematic Reviews
For adults. There is a pressing need for methodologically sound RCTs to confirm whether such interventions are helpful and, if so, for whom.
Recessive Oncogenes and Tumor Suppression
Contributors to the meeting held at the Lab in March 1989 review mapping and cloning of cancer genes, retino-blastoma, new putative tumor suppressor genes, and the ways in which interactions between viral transforming proteins and cell proteins may lead to loss of growth control. No index. Annotatio
The Art of Swordsmanship
English translation of one of the most significant medieval texts on fighting with swords.
The Radetzky March
Strauss's Radetzky March, signature tune of one of Europe's most powerful regimes, presides over Joseph Roth's account of three generations of the Trotta family in the years preceding the Austro-Hungarian collapse in 1918. Grandfather, son and grandson are equally dependent on the empire: the first for his enoblement; the second for the civil virtues that make him a meticulous servant of an administration whose failure he can neither comprehend nor survive; the third for the family standards of conduct which he cannot attain but against which he is too enfeebled to rebel.
