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Emerging Anti-cancer Compounds and Immunomodulators for Pancreatic Cancer Treatment
Pancreatic cancer is a highly lethal gastrointestinal disease that is becoming one of the leading causes of cancer mortality worldwide. Despite advances in surgery, radiation therapy, immuno-oncology, and therapeutics, the 5-year survival rate for pancreatic cancer patients remains around 12%. The poor prognosis is mainly due to late diagnosis, as pancreatic cancer patients commonly don’t exhibit symptoms until an advanced stage that is beyond surgical resection. Currently, the main treatments for patients with advanced pancreatic cancer are chemotherapy, radiotherapy, and most recent clinical trials incorporate immunotherapy.
Cancer Immunoprevention
This volume provides methods and techniques to further the study of cancer immunoprevention. Chapters describe tumor-associated antigens, cancer immune-preventive vaccines, generation of TILs, development of monoclonal antibodies, immunoprofiling technologies, tissue multispectral imaging techniques, mass cytometry on suspensions, mutiparametric flow cytometry, genomic expression analysis, and proteomic profiling of tumor microenvironment cell populations and metabolic assessment through novel imaging technologies. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Cancer Immunoprevention: Methods and Protocol aims to further understanding, development of interventional active strategies, and immune-interception of cancer.
To My Beloveds
“I could not put this book down. The stories are piercing, the counsel felt both urgent and eternal, the writing shimmers. Jen Bailey is a generational voice.”—Eboo Patel, Founder and President, IFYC and author of Acts of Faith “In this intimate and life-churning call to hope, to healing and to ourselves, Reverend Jen Bailey offers all of what makes her a leader and believer built for these times…whispering to us in every word the ancestral wisdom that we, her readers, are built for them too.”—Dawn-Lyen Gardner, Actor & Activist
Families in an Era of Increasing Inequality
The widening gap between the rich and the poor is turning the American dream into an impossibility for many, particularly children and families. And as the children of low-income families grow to adulthood, they have less access to opportunities and resources than their higher-income peers--and increasing odds of repeating the experiences of their parents. Families in an Era of Increasing Inequality probes the complex relations between social inequality and child development and examines possibilities for disrupting these ongoing patterns. Experts across the social sciences track trends in marriage, divorce, employment, and family structure across socioeconomic strata in the U.S. and other d...
