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Network Meta-Analysis for Decision-Making
A practical guide to network meta-analysis with examples and code In the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish which interventions are effective and cost-effective. Often a single study will not provide the answers and it is desirable to synthesise evidence from multiple sources, usually randomised controlled trials. This book takes an approach to evidence synthesis that is specifically intended for decision making when there are two or more treatment alternatives being evaluated, and assumes that the purpose of every synthesis is to answer the question "for this pre-identified population of patients, which treatment is 'best'?" A co...
Design and Analysis of Subgroups with Biopharmaceutical Applications
This book provides an overview of the theories and applications on subgroups in the biopharmaceutical industry. Drawing from a range of expert perspectives in academia and industry, this collection offers an overarching dialogue about recent advances in biopharmaceutical applications, novel statistical and methodological developments, and potential future directions. The volume covers topics in subgroups in clinical trial design; subgroup identification and personalized medicine; and general issues in subgroup analyses, including regulatory ones. Included chapters present current methods, theories, and case applications in the diverse field of subgroup application and analysis. Offering timely perspectives from a range of authoritative sources, the volume is designed to have wide appeal to professionals in the pharmaceutical industry and to graduate students and researchers in academe and government.
Meta-Analysis of Controlled Clinical Trials
Over the last twenty years there has been a dramatic upsurge in the application of meta-analysis to medical research. This has mainly been due to greater emphasis on evidence-based medicine and the need for reliable summaries of the vast and expanding volume of clinical research. At the same time there have been great strides in the development and refinement of the associated statistical methodology. This book describes the planning, conduct and reporting of a meta-analysis as applied to a series of randomized controlled clinical trials. * The various approaches are presented within a general unified framework. * Meta-analysis techniques are described in detail, from their theoretical devel...
Tools and Algorithms for the Construction and Analysis of Systems
This open access two-volume set constitutes the proceedings of the 26th International Conference on Tools and Algorithms for the Construction and Analysis of Systems, TACAS 2020, which took place in Dublin, Ireland, in April 2020, and was held as Part of the European Joint Conferences on Theory and Practice of Software, ETAPS 2020. The total of 60 regular papers presented in these volumes was carefully reviewed and selected from 155 submissions. The papers are organized in topical sections as follows: Part I: Program verification; SAT and SMT; Timed and Dynamical Systems; Verifying Concurrent Systems; Probabilistic Systems; Model Checking and Reachability; and Timed and Probabilistic Systems. Part II: Bisimulation; Verification and Efficiency; Logic and Proof; Tools and Case Studies; Games and Automata; and SV-COMP 2020.
China’s Footprint in East Africa
Based on an extensive literature review, in-depth interviews, fieldwork, and anecdotal evidence, this text examines China’s engagement with East Africa (notably Rwanda, Burundi, Kenya, Tanzania, and Uganda) and considers these relationships through the lens of history, diplomacy, education, trade, media, cultural exchanges, and infrastructure. It probes the sentiments of pessimism, optimism, and pragmatism to explore perceptions about China in East Africa Africa. China’s ancient connection to the East African coast, as well as other incidents of contact in the past, are analyzed from the viewpoint of the deployment of Chinese soft power capital in current times. The book notably examines the significant role China is playing in the construction of new infrastructure and housing throughout East Africa and addresses China’s involvement in the natural resources sector and the political debate surrounding the construction of gas and oil pipelines, its investment in the tourism sector, in the news media and information and communication technology sectors as well as in educational and cultural programs.
The Measurement and Analysis of Housing Preference and Choice
What are the current trends in housing? Is my planned project commercially viable? What should be my marketing and advertisement strategies? These are just some of the questions real estate agents, landlords and developers ask researchers to answer. But to find the answers, researchers are faced with a wide variety of methods that measure housing preferences and choices. To select and value a valid research method, one needs a well-structured overview of the methods that are used in housing preference and housing choice research. This comprehensive introduction to this field offers just such an overview. It discusses and compares numerous methods, detailing the potential limitation of each one, and it reaches beyond methodology, illustrating how thoughtful consideration of methods and techniques in research can help researchers and other professionals to deliver products and services that are more in line with residents’ needs.
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Framing Classical Reception Studies
Framing Classical Reception Studies contains a representative number of analytic and synthetic contributions by scholars from diverse parts of the field of Classical Reception Studies. Together, they afford a synoptic view and typology of an extremely large and continuously diversifying discipline. Attentive to questions such as what, by whom, in what contexts and to what ends Classics have functioned and are functioning in our culture, all contributors ask themselves from what conceptual or disciplinary frame they approach the reception of the cultures of classical Greek and Roman antiquity. Within this questioning format, the book also contains suggestions for future agendas of research, and forcefully argues for the political, cultural and cognitive relevance of classical receptions in the Academy.
Future of Sustainable Agriculture in Saline Environments
Food production on present and future saline soils deserves the world’s attention particularly because food security is a pressing issue, millions of hectares of degraded soils are available worldwide, freshwater is becoming increasingly scarce, and the global sea-level rise threatens food production in fertile coastal lowlands. Future of Sustainable Agriculture in Saline Environments aims to showcase the global potential of saline agriculture. The book covers the essential topics, such as policy and awareness, soil management, future crops, and genetic developments, all supplemented by case studies that show how this knowledge has been applied. It offers an overview of current research th...
