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Humoral Factors in Host Defense contains the proceedings of the First Takeda Science Foundation Symposium on Bioscience, held on October 28-30, 1982, in Kyoto, Japan. The symposium focused on the humoral factors regulating immune responses, with emphasis on T cell-derived immunoregulatory molecules; molecular mechanisms of interferons; factors involved in differentiation and activation of immunocytes; and the use of the molecular genetics approach to host defense factors. Organized into four parts encompassing 22 chapters, this volume begins with an overview of interleukin-2 and T cell-replacing factors, along with their immunological functions and biochemical features. It then discusses antigen-specific T cell factors; immunoregulatory molecules from human monoclonal T cells; physiological and pathological roles of lymphokines; regulation of the immune system by monoclonal T cell peptides; production of a glycosylated human protein by recombinant DNA technology; and molecular genetics of immunoglobulin genes and the major histocompatibility antigen. Geneticists and biologists will find this book extremely useful.
Gene Expression provides research papers on selected topics in gene expression, presented at the 11th meeting of the Federation of European Biochemical Societies, held at Copenhagen in August 1977. The book presents research knowledge provided by eminent researchers in the field of biochemistry. Each chapter contains material that is important to other researchers, such as on initiation mechanism of protein synthesis in prokaryotes; translocation mechanism of the ribosome; and analysis of ribosomal translocation by drugs. Mechanisms for the intracellular compartmentation of newly synthesized proteins; RNA synthesis and control; the sub-structure of nucleosome core particles; and future prospects on chromosome structure and function are detailed as well. The text will be of use to researchers and workers in the field of medicine, pharmacology, gene therapy, and biochemistry.
This publication provides a comprehensive account of the known groups of human tumour antigens, and the immune effector cells involved in tumour rejection. Chapters dealing with all the major groups of human tumour antigens are included, covering differentiation antigens, testes-associated antigens, CEA, mucin, viral antigens, anti-idiotypic antibodies as antigens, and fusion proteins. The role of heat shock proteins as mediators of tumour immunity is discussed and consideration is given to the immune mechanisms which mediate tumour rejection in both human and animal systems. The application of antibody targeting to identify cancers, and the mechanisms by which tumours evade immune detection and/or destruction is covered in detail. Although the focus of this publication is experimental, as with other recent publications progress in clinical immunotherapy is included in some detail, to provide postgraduate and post-doctoral scientists with in-depth reviews of the field.
Discografie van een eeuw Noord-Amerikaanse indiaanse volksmuziek en van populaire muziek van musici met indiaans bloed of met indiaanse thema's.
The Oxford Handbook of Danish Politics provides the most comprehensive and thorough English language book on Danish politics ever written. It features chapters by 50 leading experts who have contributed extensively to the field they write about. Why is Denmark an interesting topic for a Handbook? In some respects, Danish political institutions and political life are very similar to that of other small, North European countries such as the other Scandinavian countries and Netherland. However, in other respects, Danish politics is interesting in its own right. For instance, Denmark has a world record in minority governments. According to standard scholarly knowledge, this should result in unst...
Bulldozers, violent thugs, and nonviolent brokers -- The theory : state power, repression, and implications for development -- Outsourcing violence : everyday repression via thugs-for-hire -- Case studies : thugs-for-hire, repression, and mobilization -- Networks of state infrastructural power : brokerage, state penetration, and mobilization -- Brokers in harmonious demolition : mass mobilizers, mediators, and huangniu -- Comparative context : South Korea and India.
This book is about melanoma—its biology, immunology, and pathology, as well as the initial use of powerful genomic tools to study its fundamental mole- lar and genetic characteristics. The study of cancer will be profoundly impacted by the Human Genome Project. I would like to discuss some of these changes. The first draft of the human genome sequence was announced in June 2000, and we have just scratched the surface of the changes it will engender in medicine. A relevant question is what are the long-term effects of the Human Genome Project for medicine? I would argue that there are three, and each of these three point toward the view that systems biology will dominate biology and medicin...
This book is an important contribution to our understanding of food in China through an ethnographic case study of an alternative food movement in Shanghai and the surrounding countryside. Cody examines a group of middle-class urban residents who move to the countryside to establish small-scale and independent organic farms. The book explores the complex relationships movement protagonists have with customers in the city, rural neighbours in the countryside, volunteers on their farms, intellectuals involved in rural reconstruction initiatives as well as the organic items they produce. In doing so, Cody provides valuable insights into the urban/rural dichotomy and questions of morality in China today. This book speaks to several concerns associated with the accelerated modernization China and other Asian nations are experiencing, including food safety and class relations. It will appeal to scholars and practitioners across a range of fields including anthropology, food studies, rural development and China Studies.
This book is about the escape strategies used by cancer cells to avoid the immune response of the host. The main characters of this story are the “Antigen Presenting Molecules” and the “T Lymphocytes”. The former are known as the Major Histocompatibility Complex (MHC): the H-2 and the HLA molecules. The latter are a subgroup of white cells travelling all over our body which are capable to distinguish between “self and non self”. Readers will know from the inside about the history of the HLA genetic system and will discover how T lymphocytes recognize and destroy cancer cells. One of the key important questions is: Why tumors arise, develop and metastasize? This book tries to answ...
Safety and Efficacy of Radiopharmaceuticals was established as a very important and comprehensive subject at the First Europe an Symposium on Radiopharmacy and Radiopharmaceuticals in Denmark in 1983. The interest in this subject has grown considerably since then due to the growing interest among national authorities to deal with radiopharmaceuticals. The introduction in recent years of nuclear medicine techniques based on radioactive labelled cells and on monoclonal antibodies has stressed the importance of a well functioning approval system for the clinical trial and use of new radiopharmaceuticals. The process of transferring the experience from the non radioactive drug field into the are...