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Stem Cell Bioprocessing
  • Language: en
  • Pages: 236

Stem Cell Bioprocessing

  • Type: Book
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  • Published: 2013-11-15
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  • Publisher: Elsevier

Stem cell bioprocessing describes the main large-scale bioprocessing strategies for both stem cell culture and purification, envisaging the application of these cells for regenerative medicine and drug screening. Bioreactor configurations are described, including their applications for stem cell expansion, and stem cell separation techniques such as isolation and purification are discussed. Basic definitions are provided concerning the different types of stem cells, from adult stem cells to the more recent induced pluripotent stem cells. The main characteristics of these different stem cell types are described, alongside the molecular mechanisms underlying their self-renewal and differentiat...

Engineering Strategies for Regenerative Medicine
  • Language: en
  • Pages: 284

Engineering Strategies for Regenerative Medicine

Engineering Strategies for Regenerative Medicine considers how engineering strategies can be applied to accelerate advances in regenerative medicine. The book provides relevant and up-to-date content on key topics, including the interdisciplinary integration of different aspects of stem cell biology and technology, diverse technologies, and their applications. By providing massive amounts of data on each individual, recent scientific advances are rapidly accelerating medicine. Cellular, molecular and genetic parameters from biological samples combined with clinical information can now provide valuable data to scientists, clinicians and ultimately patients, leading to the development of preci...

Stem Cell Manufacturing
  • Language: en
  • Pages: 342

Stem Cell Manufacturing

  • Type: Book
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  • Published: 2016-07-24
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  • Publisher: Elsevier

Stem Cell Manufacturing discusses the required technologies that enable the transfer of the current laboratory-based practice of stem cell tissue culture to the clinic environment as therapeutics, while concurrently achieving control, reproducibility, automation, validation, and safety of the process and the product. The advent of stem cell research unveiled the therapeutic potential of stem cells and their derivatives and increased the awareness of the public and scientific community for the topic. The successful manufacturing of stem cells and their derivatives is expected to have a positive impact in the society since it will contribute to widen the offer of therapeutic solutions to the p...

Multiphase Bioreactor Design
  • Language: en
  • Pages: 550

Multiphase Bioreactor Design

  • Type: Book
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  • Published: 2001-09-20
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  • Publisher: CRC Press

Bioreaction engineering is fundamental to the optimization of biotechnological processes and the production of biochemicals by enzymes, microbial, plant and animal cells and higher organisms. A reference text for postgraduate students and researchers in biochemical engineering and bioreactor design, Multiphase Bioreactor Design describes the

Applied Biocatalysis
  • Language: en
  • Pages: 492

Applied Biocatalysis

  • Type: Book
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  • Published: 2003-09-02
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  • Publisher: CRC Press

This book describes the essential steps in the development of biocatalytic processes from concept to completion. It is a carefully integrated text which combines the fundamentals of biocatalysis with technological experience and in-depth commercial case studies. The book starts with an introductory look at the characteristics and present applications of biocatalysts, followed by more detailed overviews of these areas.

Stem Cell Bioprocessing and Manufacturing
  • Language: en
  • Pages: 170

Stem Cell Bioprocessing and Manufacturing

  • Type: Book
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  • Published: 2021-01-20
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  • Publisher: MDPI

The next healthcare revolution will apply regenerative medicines using human cells and tissues. The aim of the regenerative medicine approach is to create biological therapies or substitutes in vitro for the replacement or restoration of tissue function in vivo lost through failure or disease. However, whilst science has revealed the potential, and early products have shown the power of such therapies, there is an immediate and long-term need for expertise with the necessary skills to face the engineering and life science challenges before the predicted benefits in human healthcare can be realized. Specifically, there is a need for the development of bioprocess technology for the successful ...

Um homem de caracter
  • Language: en
  • Pages: 88

Um homem de caracter

  • Type: Book
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  • Published: 1931
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  • Publisher: Unknown

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Bioreactors for Stem Cell Expansion and Differentiation
  • Language: en
  • Pages: 260

Bioreactors for Stem Cell Expansion and Differentiation

  • Type: Book
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  • Published: 2018-09-03
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  • Publisher: CRC Press

An international team of investigators presents thought-provoking reviews of bioreactors for stem cell expansion and differentiation and provides cutting-edge information on different bioreactor systems. The authors offer novel insights into bioreactor-based culture systems specific for tissue engineering, including sophisticated and cost-effective manufacturing strategies geared to overcome technological shortcomings that currently preclude advances towards product commercialization. This book in the fields of stem cell expansion, bioreactors, bioprocessing, and bio and tissue engineering, gives the reader a full understanding of the state-of-art and the future of these fields. Key selling features: Describes various bioreactors or stem cell culturing systems Reviews methods for stem cell expansion and differentiation for neural, cardiac, hemopoietic, mesenchymal, hepatic and other tissues cell types Distinguishes different types of bioreactors intended for different operational scales of tissue engineering and cellular therapies Includes contributions from an international team of leaders in stem cell research

Stem Cell Bioprocessing and Manufacturing
  • Language: en
  • Pages: 170

Stem Cell Bioprocessing and Manufacturing

  • Type: Book
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  • Published: 2020
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  • Publisher: Unknown

The next healthcare revolution will apply regenerative medicines using human cells and tissues. The aim of the regenerative medicine approach is to create biological therapies or substitutes in vitro for the replacement or restoration of tissue function in vivo lost through failure or disease. However, whilst science has revealed the potential, and early products have shown the power of such therapies, there is an immediate and long-term need for expertise with the necessary skills to face the engineering and life science challenges before the predicted benefits in human healthcare can be realized. Specifically, there is a need for the development of bioprocess technology for the successful ...

Computer and Information Science Applications in Bioprocess Engineering
  • Language: en
  • Pages: 469

Computer and Information Science Applications in Bioprocess Engineering

Biotechnology has been labelled as one of the key technologies of the last two decades of the 20th Century, offering boundless solutions to problems ranging from food and agricultural production to pharmaceutical and medical applications, as well as environmental and bioremediation problems. Biological processes, however, are complex and the prevailing mechanisms are either unknown or poorly understood. This means that adequate techniques for data acquisition and analysis, leading to appropriate modeling and simulation packages that can be superimposed on the engineering principles, need to be routine tools for future biotechnologists. The present volume presents a masterly summary of the most recent work in the field, covering: instrumentation systems; enzyme technology; environmental biotechnology; food applications; and metabolic engineering.