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Muscarinic Receptors in Airways Diseases
What are the different muscarinic acetylcholine receptor subtypes and how are they distributed in the airways and molecular signalling mechanisms? What is their function in neurogenic and non-neurogenic control of the airways and in inflammatory mechanisms? How is their gene expression regulated? The great importance of muscarinic acetylcholine receptors for the pathophysiology and treatment of chronic inflammatory obstructive airways diseases calls for a comprehensive and integrated overview of the current knowledge to address such questions, to discuss the role of these receptor subtypes in diseases such as asthma and COPD, and to present novel perspectives on antimuscarinic drug development. The present book is the worthy result of this need. It points out innovative insights into the hitherto poorly understood role of postjunctional muscarinic M2 receptors in airway smooth muscle contraction and sheds some light on the novel concepts of antimuscarinic drug development, with special reference to the l
Adrenoceptors
None
Inflammatory Cells and Mediators in Bronchial Asthma
Inflammatory Cells and Mediators in Bronchial Asthma provides reviews and summaries regarding state-of-the-art articles that examine the role of various inflammatory cells and their mediators in the pathogenesis of asthma. Topics include pharmacological and biochemical regulation of the airways; involvement of key inflammatory cells and the release and effect of their mediators in airway function; and the characteristics of receptors for leukotriene B4, C4, and D4, adenosine, platelet-activating factor, sensory and inflammatory peptides, and the effect of various anti-asthmatic drugs on airway inflammation. Physicians, allergists, immunologists, and pulmonary disease research scientists will find this book to be an invaluable reference resource.
The American Review of Respiratory Disease
Includes Abstracts section, previously issued separately.
AJRCCM
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Catecholamines
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''Sa Wie It''
We are a nation of immigrants, but every story is unique. This family story is rooted in prewar Netherlands and the German occupation, it continues in South Africa, and comes to maturity in the United States. It is the story of the Riemersma family. George Riemersma now lives in Sheboygan, Wisconsin, with Rita, his wife of almost 62 years. He can be contacted at: griemersma@excel.net
