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Overall, American blacks have twice the rate of high blood pressure of American whites and five to seven times the rate of severe hypertension. As a result, American blacks have a higher incidence of stroke (50%), heart disease (30%), and kidney disease (50%). Not only are blacks more likely to develop hypertension, but the disorder develops earlier, is often more severe, and is more likely to be fatal at an earlier age. While lack of early and aggressive treatment contributes to the problem, research has shown that physiological and environmental factors play an important role. Pathophysiology of Hypertension in Blacks examines much of the research that has been done to explain the pathogen...
Each issue includes a classified section on the organization of the Dept.
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Each issue includes a classified section on the organization of the Dept.
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Exactly sixty years ago Schretzenmayer provided the first experimental proof that changes in blood ftow can affect the diameter oflarge arteries. Since then, support has been growing for the idea that intraluminal blood ftow plays an important role in regulating not only the tone of blood vessels, but also their caliber and structure. Investigations of the&e phenomena have been given a strong impetus by the discovery that the endothelium can modulate the tone of underlying vascular smooth muscle via the release of a number of vasoactive substances. Investigators often diverge in their opinions regarding the nature of the vascular wall response to blood ftow and the mechanisms involved. This ...
First multi-year cumulation covers six years: 1965-70.
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