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Muscular contraction provides one of the most fascinating topics for a biophysicist to study. Although muscle comprises a molecular machine whereby chemical energy is converted to mechanical work, its action in producing force is something that is readily observable in everyday life, a feature that does not apply to most other structures of biophysical inter est. In addition, muscle is so beautifully organized at the microscopic level that those important structural probes, electron microscopy (with the associated image analysis methods) and X-ray diffraction, have pro vided a wealth of information about the arrangements of the constituent proteins in a variety of muscle types. But, despite ...
J.C. Squire (1884-1958) bestrode the literary world of the inter-war era like a colossus. A poet, journalist, editor of the New Statesman and presiding genius of the London Mercury, he was much adored and - as a combative traditionalist - much reviled. Evelyn Waugh satirised him in Decline and Fall.
First multi-year cumulation covers six years: 1965-70.
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Sliding Filament Mechanism in Muscle Contraction: Fifty Years of Research covers the history of the sliding filament mechanism in muscle contraction from its discovery in 1954 by H.E. Huxley through and including modern day research. Chapters include topics in dynamic X-ray diffraction, electron microscopy, muscle mechanisms, in-vitro motility assay, cardiac versus smooth muscle, motile systems, and much more.