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Murder--and chemical warfare--most foul.
An acknowledged expert on the history of modern pharmacology and drug therapy, John Parascandola here brings together 19 of his most important papers on these subjects. The book is divided into three topical sections. In the first group of articles, devoted to pharmacological theory, Dr. Parascandola sheds new light on our understanding of the history of such key pharmacological concepts as receptor theory, structure-activity relationships, and the role of stereochemistry in physiological action. The second section focuses on the discipline of pharmacology and offers insights into the pivotal role played by John J. Abel in the shaping of the field, the development of pharmacology in schools of pharmacy and in the Federal Government, and the national pharmacological society's membership ban on pharmacologists working in industry. The final section on drug therapy discusses various drugs from antibiotics to sulfones, and their use in the treatment of diseases such as leprosy and syphilis.
Growing public interest in animal welfare issues in recent decades has prompted increased attention to the efforts to develop alternative, nonanimal methods for use in biomedical research and product testing. In A History of the Development of Alternatives to Animals in Research and Testing, the first book-length study of the subject, John Parascandola traces the history of the concept of alternatives to the use of animals in research and testing in Britain and the United States from its beginnings until it had become firmly established in the scientific and animal protection communities by the end of the 1980s. This account of the history of alternatives is set within the context of developments within science, animal welfare, and politics. The book covers the key role played by animal welfare advocates in promoting alternatives, the initial resistance to alternatives on the part of many in the scientific community, the opportunity provided by alternatives for compromise and cooperation between these two groups, and the dominance of the “Three Rs”—reduction, refinement, and replacement.
Adds 21 new essays and drops some that appeared in the 1984 edition (first in 1978) to reflect recent scholarship and changes in orientation by historians. Adds entirely new clusters on sickness and health, early American medicine, therapeutics, the art of medicine, and public health and personal hygiene. Other discussions are updated to reflect such phenomena as the growing mortality from HIV, homicide, and suicide. No index. Annotation copyrighted by Book News, Inc., Portland, OR
A comprehensive look at the beginnings of the current drug problems in the United States Federal Drug Control: The Evolution of Policy and Practice presents an overview of the key issues and key individuals responsible for the creation of the federal government’s efforts to control illegal drugs in the United States, from 1875-2001. The book focuses special attention on federal legislation that constructed the federal drug regulatory machinery and the Supreme Court cases that interpreted these laws and their implementation. An esteemed panel of scholars, including co-editor Joseph Spillane, author of Cocaine: From Medical Marvel to Modern Menace, and William B. McAllister, author of Drug D...
A collection of essays exploring the complex history of drugs and narcotics throughout historyfrom ancient Greece to the present dayshows that such substances were sought originally as healing agents, both within and without the medical profession. However, the mood- and mind-altering characteristics of some have led to the widespread abuse and legal controls we see today.
Standardizing Pharmacology: Assays and Hormones, Volume Two in the Discoveries in Pharmacology series, presents selected articles from historic discoveries that are enhanced with commentary from contemporary scholars who present discussions on the importance of each chapter, along with an updated bibliography on the subject and contributions from a Nobel Prize winner and other pioneers in pharmacology. Academic and industry researchers in pharmacology and medicine, as well as advanced students will find this series a useful teaching tool and launch to new discoveries. Sections cover key discoveries in receptor theory, pharmacological methods and the development of hormone therapy, including ...
First multi-year cumulation covers six years: 1965-70.