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The Neuropathology of Dementia
Completely rewritten and updated, this new edition is almost twice the size of its predecessor. Illustrated in colour throughout, and with contributions from the world's leading authorities, it is the definitive reference on the neuropathology of dementia. It gives practical guidance to pathologists, describes the contribution of neuroimaging to diagnosis, and surveys the clinical features of dementia. New material includes: Three entirely new chapters on neuroimaging, molecular diagnostics, and transgenic models. Two chapters on tauopathies under new authorship. A chapter under new authorship on synucleinopathies, which includes multiple system atrophy.
Limbic-predominant Age-related TDP-43 Encephalopathy
Book 9 focuses on a new dementia type, LATE, mistaken as Alzheimer's disease until now.LATE stands for Limbic-predominant age-related TDP-43 encephalopathy, the protein buildup responsible for this dementia. This book is organic, like the series, meaning we never consider our books as finished. Science evolves, which is why our books go through continuous updates. Since LATE is a new dementia classification, we expect continuous further information to emerge. Watch Amazon alerts for potential digital updates. We provide free digital copies on all paperback purchases, so everybody receives free updates.
What If It's Not Alzheimer's?
Although the public most often associates dementia with Alzheimer’s disease, the medical profession continues to advance distinctions of various types of “other” dementias. What If It’s Not Alzheimer’s? is the first and remains the only comprehensive guide dealing with frontotemporal degeneration (FTD), the most common form of dementia for people under 60 years of age. The contributors are either specialists in their fields or have exceptional hands-on experience with FTD sufferers. Beginning with a focus on the medical facts, the first part defines and explores FTD as an illness distinct from Alzheimer's disease. Also considered are clinical and medical care issues and practices, ...
Aging and the Gastrointestinal Tract
With the dramatic increase of the aging population, the study and care of gastrointestinal disorders in the elderly have become priority topics for both clinicians and researchers. The geriatric approach which includes the epidemiology and pharmacokinetics of drugs as well as a comprehensive multidimensional assessment is particularly important in managing older patients with gastrointestinal disorders, since these patients are likely to have multiple interacting problems that interfere with their daily function and complicate their treatment. This book presents the results of recent studies in geriatric gastroenterology and reviews both basic and clinical aspects of the field. An important ...
Neuroimmune System
The book explores the intricate connections between the nervous and immune systems in the context of neurodegenerative disorders, offering a comprehensive overview of the bidirectional communication between these systems and their implications for disease progression and therapeutic interventions. The book aims to understand the recent developments in the field of neuroimmune communication. Key Features: In-depth analysis of immunological biomarkers and therapeutic targets for neurodegenerative disorders. Exploration of the role of glial cells in neuroimmune interactions and their dual nature in disease pathology. Examination of short- and long-range interactions between the central nervous ...
Vision in Alzheimer's Disease
Visual dysfunction is prevalent in Alzheimer's disease and in related disorders such as posterior cortical atrophy and Down syndrome. The neuropathology of these disorders affects brain areas that process low-level vision as well as higher-order cognition and attention. This volume spans the range of topics on vision, from structure (retinal and cortical) to function (cortical activation) to behavior (perception, cognition, attention, hallucinations, and everyday activities). The chapters together indicate that lower-level visual deficits can contribute to, or masquerade as, higher-order cognitive impairments. As important, they suggest that vision-based interventions may improve patients' l...
Autonomic Nervous System in Old Age
With the remarkable increase in life expectancy in recent years, overall numbers of older individuals living with disability and functional dependence are likely to increase. Age-related changes and diseases involving the peripheral nervous system, particularly its autonomic elements, frequently play determining roles in late life health and functional independence. While basal sympathetic activity increases with normative aging, there is evidence of considerable dysregulation of the ability of the aging sympathetic nervous system to respond to a variety of challenges. In this book, investigators from several different disciplines discuss aging of the autonomic nervous system from a variety of perspectives. Given the fact that aging of the parasympathetic elements of the autonomic nervous system is not nearly as well understood as that of its sympathetic portions, greater emphasis has been placed on the latter. The topics of this volume provide an excellent overview addressing a number of clinically important questions by highlighting key clinical and basic research studies. This book should be of great interest for general physicians, specialists in geriatrics, and neurologists.
Essentials of Rubin's Pathology
Essentials of Rubin's Pathology, Fifth Edition is a condensed version of Rubin's widely acclaimed pathology text, targeted to students in allied health fields, including dentistry, nursing, physical therapy, and occupational therapy. Essentials of Rubin's Pathology has the same outline of 30 chapters as Rubin's Pathology, 10 chapters covering principles and mechanisms of pathology and 20 covering organ-specific pathology. Essentials extracts key information on pathogenesis, epidemiology, and clinical features of diseases and contains over 800 schematic illustrations and photographs derived from Rubin's Pathology. A companion Website will offer the fully searchable online text, case studies, audio review questions, Podcasts, and an image bank and test generator for faculty.
Management of Aging
One of the world's major geriatric departments is housed in the Geneva University Hospital and has a 36-year-old history behind it. Some of its developments are set out in this book. Care programs such as geriatric concepts of care, community based support, convalescent beds, memory clinics, palliative medicine and care and practice of clinical ethics are discussed. Research has focussed on 15 years of comparative cross-sectional studies on aging in an urban and a rural area of Switzerland, prevalence of dementia in Geneva and Zurich, clinico-neuropathological correlation, fall prevention, hip fracture outcomes and the impact of nutrition on the recovery of hip fractures. Teaching activities...
