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Novel Treatments and the Underlying Mechanisms for Diabetic Foot and Related Diseases
Diabetic foot is a serious complication of diabetes worldwide. The etiology of diabetic foot is quite complex due to its multifactorial nature. Diabetic neuropathy, peripheral artery disease, foot deformity, high blood glucose and secondary infection all can contribute to diabetic foot ulceration and gangrene, sometimes resulting in minor or major amputations. Several risk factors including old age, long-term diabetes, smoking, foot deformity, and ischemia have been identified in diabetic foot. Many diagnostic methods are used for early-stage diabetic neuropathy and peripheral arterial disease, such as pulse wave, ankle-brachial artery ratio, Sudoscan, gait analysis, etc. Due to the high glucose environment, metabolic disorder, ischemia and peripheral neuropathy, diabetic foot ulcer is much more difficult to heal than common traumatic wounds. Therefore, in addition to existing treatments, new methods or techniques are still needed to improve wound healing. We also expect to find novel pathways to elucidate the complicated mechanisms involved in diabetic foot and diabetic wound healing.
Drug-induced and Iatrogenic Respiratory Disease
At the present time, 430 drugs are known to cause respiratory injury. This represents an increase of almost 200 in the last ten years, and the number is still increasing. This comprehensive, definitive reference work, with an outstanding range of international expert contributors and two of the world's leading editors, provides an essential reference for the practising respiratory physician. Key features: The text builds upon basics with a review of basic sciences. The book covers imaging, varied drug-induced interstitial lung disease including pulmonary edema and diffuse alveolar hemorrhage, acute respiratory failure, pleural involvement and upper to lower airway disease A wide range of dis...
