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Extracellular Vesicles and Their Importance in Human Health
  • Language: en
  • Pages: 172

Extracellular Vesicles and Their Importance in Human Health

Extracellular vesicle is a wide term that involves many different types of vesicles. Almost all the cell types studied secrete vesicles to the extracellular environment related to cell - cell communication. Extracellular vesicles have been found in different biological fluids, such as blood, milk, saliva, tears, urine, and cerebrospinal fluid. These vesicles transport different molecules, including mRNA, proteins, and lipids, some of them cell type specific that make them ideal biomarkers in both health and disease conditions. However, their contribution to different conditions is not well understood. The aim of this book is to provide an overview of the extracellular vesicles in the human body, how they are internalized, and their participation in several diseases.

Immunity to Human Fungal Pathogens: Mechanisms of Host Recognition, Protection, Pathology, and Fungal Interference
  • Language: en
  • Pages: 440

Immunity to Human Fungal Pathogens: Mechanisms of Host Recognition, Protection, Pathology, and Fungal Interference

Fungi are found in virtually every environment, and comprise a significant portion of the normal microflora of healthy individuals. Some species of fungi are aeroallergen sources capable of inducing sensitization and causing exacerbation of asthma and respiratory allergy. Others are transmissible between hosts and may cause no symptoms in healthy individuals. However, immune suppressed individuals may develop invasive disease marked by tissue invasion with a potential for widespread dissemination. Existing therapies for patients consist of antifungal drugs, yet these require prolonged administration with the possibility of adverse side effects, and may be rendered ineffective by the emergenc...

A Companion to Calderón de la Barca
  • Language: en
  • Pages: 414

A Companion to Calderón de la Barca

The first comprehensive study of Calderón in EnglishPedro Calderón de la Barca (1600-1681) is one of the most important dramatists - many would say the single most important dramatist - of the Spanish Golden Age. Spain''s dominant and most prestigious playwright for much of the seventeenth century, his work is still regularly staged and translated, influential in more recent times on writers as diverse as Schiller, Shelley and Lorca. The author of around 120 plays (not counting his numerous Corpus Christi autos) in a variety of styles, Calderón is most famous for his stirring dramas, characterized by rhetorically powerful poetry, dramatic structures carefully calibrated to produce poignan...

Kings in Calderón
  • Language: en
  • Pages: 166

Kings in Calderón

  • Type: Book
  • -
  • Published: 1986
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  • Publisher: Tamesis

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The Art of Humour in the Teatro Breve and Comedias of Calderón de la Barca
  • Language: en
  • Pages: 262

The Art of Humour in the Teatro Breve and Comedias of Calderón de la Barca

Frantic and popular characters and situations from the entremes tradition, thought by many as opposing the comedias' main features, are instead shown to join and often dominate these features through the introduction of absurd figuras, slapstick, and burlas."--BOOK JACKET.

How to Write the History of the New World
  • Language: en
  • Pages: 490

How to Write the History of the New World

An Economist Book of the Year, 2001. In the 18th century, a debate ensued over the French naturalist Buffon’s contention that the New World was in fact geologically new. Historians, naturalists, and philosophers clashed over Buffon’s view. This book maintains that the “dispute” was also a debate over historical authority: upon whose sources and facts should naturalists and historians reconstruct the history of the New World and its people. In addressing this question, the author offers a strikingly novel interpretation of the Enlightenment.

Pedro Calderón de la Barca
  • Language: en
  • Pages: 315

Pedro Calderón de la Barca

This is a definitive critical edition of the holograph manuscript (1639) of Calderón’s comedy. This volume traces the textual history of the play and lists variants from all known editions printed in or immediately after Calderón’s lifetime; it also gives a brief account of editions printed up to the end of the eighteenth century. Two sets of notes are provided: one listing and discussing all the emendations, additions and deletions made by Calderón in the course of the composition of the play; and the other offering clarification of words and allusions in the text which might cause difficulty for the modern reader.

Applied Emblems in the Cathedral of Lugo
  • Language: en
  • Pages: 509

Applied Emblems in the Cathedral of Lugo

  • Type: Book
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  • Published: 2021-02-08
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  • Publisher: BRILL

In Applied Emblems in the Cathedral of Lugo, Carme López Calderón explores the emblematic programme found in the Chapel of Nuestra Señora de los Ojos Grandes (Galicia, Spain), consisting of fifty-eight emblems painted c. 1735. Making use of a wide range of printed sources, the author delves into the meaning of each emblem and provides an all-encompassing interpretation of this cycle, which can rightly be described as the richest and most complete programme of Marian applied emblematics in the Iberian Peninsula.

Recent Developments in Real and Harmonic Analysis
  • Language: en
  • Pages: 215

Recent Developments in Real and Harmonic Analysis

A collection of invited chapters dedicated to Carlos Segovia, this unified and self-contained volume examines recent developments in real and harmonic analysis. The work begins with a chronological description of Segovia’s mathematical life, highlighting his original ideas and their evolution. Also included are surveys dealing with Carlos’ favorite topics, and PDE works written by students and colleagues close to Segovia whose careers were in some way influenced by him. Contributors: H. Aimar, A. Bonami, O. Blasco, L.A. Caffarelli, S. Chanillo, J. Feuto, L. Forzani, C.E. Gutíerrez, E. Harboure, A.L. Karakhanyan, C.E. Kenig, R.A. Macías, J.J. Manfredi, F.J. Martín-Reyes, P. Ortega, R. Scotto, A. de la Torre, J.L. Torrea.

Deconstructing Legitimacy
  • Language: en
  • Pages: 418

Deconstructing Legitimacy

The overthrow of Viceroy Joaqu&ín de la Pezuela on 29 January 1821 has not received much attention from historians, who have viewed it as a simple military uprising. Yet in this careful study of the episode, based on deep archival research, Patricia Marks reveals it to be the culmination of decades of Peruvian opposition to the Bourbon reforms of the late eighteenth century, especially the Reglamento de comercio libre of 1778. It also marked a radical change in political culture brought about by the constitutional upheavals that followed Napolean's invasion of Spain. Although Pezuela's overthrow was organized and carried out by royalists among the merchants and the military, it proved to be an important event in the development of the independence movement as well as a pivotal factor in the failure to establish a stable national state in post-independence Peru. The golpe de estado may thereby be seen as an early manifestation of Latin American praetorianism, in which a sector of the civilian population, unable to prevail politically and unwilling to compromise, pressures army officers to act in order to &"save&" the state.