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Microarray Bioinformatics
This book is a comprehensive guide to all of the mathematics, statistics and computing you will need to successfully operate DNA microarray experiments. It is written for researchers, clinicians, laboratory heads and managers, from both biology and bioinformatics backgrounds, who work with, or who intend to work with microarrays. The book covers all aspects of microarray bioinformatics, giving you the tools to design arrays and experiments, to analyze your data, and to share your results with your organisation or with the international community. There are chapters covering sequence databases, oligonucleotide design, experimental design, image processing, normalisation, identifying differentially expressed genes, clustering, classification and data standards. The book is based on the highly successful Microarray Bioinformatics course at Oxford University, and therefore is ideally suited for teaching the subject at postgraduate or professional level.
The TRANSMED Atlas. The Mediterranean Region from Crust to Mantle
A publication of the Mediterranean Consortium for the 32nd International Geological Congress
The Mediterranean Diet
The Mediterranean Diet offers researchers and clinicians a single authoritative source which outlines many of the complex features of the Mediterranean diet: ranging from supportive evidence and epidemiological studies, to the antioxidant properties of individual components. This book embraces a holistic approach and effectively investigates the Mediterranean diet from the cell to the nutritional well-being of geographical populations. This book represents essential reading for researchers and practicing clinicians in nutrition, dietetics, endocrinology, and public health, as well as researchers, such as molecular or cellular biochemists, interested in lipids, metabolism, and obesity. - Presents one comprehensive, translational source for all aspects of how the Mediterranean diet plays a role in disease prevention and health - Experts in nutrition, diet, and endocrinology (from all areas of academic and medical research) take readers from the bench research (cellular and biochemical mechanisms of vitamins and nutrients) to new preventive and therapeutic approaches - Features a unique section on novel nutraceuticals and edible plants used in the Mediterranean region
Ostracoda in the Earth Sciences
Ostracods belong to a group of microfossils found in nearly all types of aquatic environments. These microcrustaceans, characterized by a bivalved, calcitic carapace, are used to reconstruct ancient environments. For example, they can help to provide information on palaeoclimates, palaeogeography, the formation of deep oceans, sea level changes, etc. This book endeavours to bring about a greater understanding of their usefulness in many aspects of geological sciences, and provides suggestions for future research. It is principally intended for the non-specialist, and shows many applications of ostracods to help solve geological problems and phenomena. Topics reviewed assume no prior knowledge of palaeontology, and thus terminology is kept simple. There is an exhaustive index, and an appendix supplying additional references on significant sources of information on ostracods. This book aims to deliver information on ostracods to those people not usually interested in the literature of palaeontology and also to awaken an interest in the Ostracoda by referring to more specialized articles published elsewhere.
The Physiology of Characean Cells
This book describes the unique characean experimental system, which provides a simplified model for many aspects of the physiology, transport and electrophysiology of higher plants. The first chapter offers a thorough grounding in the morphology, taxonomy and ecology of Characeae plants. Research on characean detached cells in steady state is summarised in Chapter 2, and Chapter 3 covers characean detached cells subjected to calibrated and mostly abiotic types of stress: touch, wounding, voltage clamp to depolarised and hyperpolarised potential difference levels, osmotic and saline stress. Chapter 4 highlights cytoplasmic streaming, cell-to-cell transport, gravitropism, cell walls and the role of Characeae in phytoremediation. The book is intended for researchers and students using the characean system and will also serve as an invaluable reference resource for electrophysiologists working on higher plants.
Telomeres and Telomerase
Telomeres are essential functional elements of eukaryotic chromosomes. Their fundamental biological role as protectors of chromosome stability was identified for the first time in the 1930s by Hermann Muller and Barbara McClintock based on pioneering cytological experiments. Modern molecular research carried out more recently revealed that telomeres and telomerase play important roles in processes such as carcinogenesis and cellular senescence. This special issue presents the most recent developments in this highly active field of research. It is becoming increasingly clear that molecular pathways involved in regulation of telomere length and structure are functionally linked with pathways involved in DNA damage response, cellular stress response, chromatin organization and perhaps even pathways that regulate evolutionary chromosome rearrangements. The above functional link is explored by the leading experts in the field of telomere biology. Cell biologists, molecular biologists, oncologists, gerontologists, and radiobiologists with an interest in the role of telomeres/telomerase will appreciate the up-to-date information in this publication.
Carbonates in Continental Settings
This book provides an up-to-date compilation of the latest research on the petrography, facies, paleonvironmental significance and economic aspects of continental carbonates. The overall organization of the book first emphasizes the descriptive aspects and processes operating on carbonate deposits in greatly varied settings, and then considers applications for basin analysis, as well as economic and historical aspects. This volume will be a valuable tool for graduate and postgraduate students as well as for experienced researchers. The second part (volume 62 in this series) will deal with the geochemistry, diagenesis and applications of carbonates in continental settings. - Covering the greatly varied aspects of carbonate deposits from continental settings deposits - Clear and easy to follow organization - Up to date information, so readers can find references from the classic literature to the most recent research
