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Medical Product Safety Evaluation: Biological Models and Statistical Methods presents cutting-edge biological models and statistical methods that are tailored to specific objectives and data types for safety analysis and benefit-risk assessment. Some frequently encountered issues and challenges in the design and analysis of safety studies are discussed with illustrative applications and examples. Medical Product Safety Evaluation: Biological Models and Statistical Methods presents cutting-edge biological models and statistical methods that are tailored to specific objectives and data types for safety analysis and benefit-risk assessment. Some frequently encountered issues and challenges in t...
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To accompany the hugely sccessful 'Methods for Economic Evaluation of Health Care Programmes 2e', this book is a thorough and rigourous discussion of the methodological principles and recent advances in the rapidly advancing field of theory and practice of economic evaluation in health care. Written by an internationally acclaimed group of authors, the book provides an in-depth discussion of the latest theoretical advances and gives comprehensive reviews of the available literature. The book covers the main areas of economic evaluation, including the methods for measuring costs and outcomes, the collection of data alongside clinical studies, ways of handling uncertainty, discounting and issues relating to the transferability of economic data. It is an ideal book for those studying economic evaluation on postgraduate or professional courses in health economics or public health.
Appendix 42 in the report of the minister of agriculture for 1874 consists of a Report of proceedings connected with Canadian archives in Europe, by H.A.J.B. Verreau.
This book constitutes the second volume of interviews with prominent mathematicians and mathematical scientists who visited the Institute for Mathematical Sciences, National University of Singapore. First published in the Institute's newsletter Imprints during the period 2010-2020, they offer glimpses of an esoteric universe as viewed and experienced by some of the leading and creative practitioners of the craft of mathematics.The topics covered in this volume are wide-ranging, running from pure mathematics (logic, number theory, algebraic geometry) to applied mathematics (mathematical modeling, fluid dynamics) through probability and statistics, mathematical physics, theoretical computer sc...
Includes entries for maps and atlases.
Combines recent developments in resampling technology (including the bootstrap) with new methods for multiple testing that are easy to use, convenient to report and widely applicable. Software from SAS Institute is available to execute many of the methods and programming is straightforward for other applications. Explains how to summarize results using adjusted p-values which do not necessitate cumbersome table look-ups. Demonstrates how to incorporate logical constraints among hypotheses, further improving power.