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The overall incidence of meningiomas, particularly in the developed countries, is rising due to a growing size of the aging population, with people living longer and enjoying healthier lives than ever before. Additionally, an increased utilization of imaging studies such as computer tomography (CT) and magnetic resonance (MR) for routine evaluation of closed head injuries, paranasal sinus problems and various non-specific neurological symptoms, ranging from headaches to dizziness, has contributed to enhanced detection of incidental meningiomas. The book contains the most up-to-date information in all matters related to meningiomas, and is written by multiple contributors - internationally recognized experts in their respective fields from Asia, USA and Europe. This is an essential reference guide to neurosurgeons and neurologists (in training and in practice), as well as medical libraries, throughout the world.
In this book, the author provides expert analysis on naturally occurring iridoids, their chemistry and their distribution in plants and insects. Particular attention is given to the pharmacology of iridoids and their prospective applications in pharmaceutical and agricultural industries. Iridoids are found in a wide variety of plants and some insects, and they are structurally derived from monoterpenoid natural products. In the first two chapters of this book, the author describes the iridoids classification, occurrence and distribution in plants and insects. The following chapters cover different chromatographic and spectroscopic techniques that can be used to identify and quantify iridoids...
An ideal resource for board exam preparation, this review distills the essentials of neurosurgery in a user-friendly question and answer format. Divided into three main sections, this text presents a comprehensive collection of cases covering intracranial pathology, spinal and peripheral nerve pathology, and neurology. Each chapter opens by detailing the clinical presentation of a problem frequently encountered in everyday practice followed by a list of questions and answers designed to test the reader's knowledge of diagnostic techniques, imaging, surgical indications, treatment options, potential complications, and outcomes.Highlights: Contributions from internationally recognized authorit...
Neuro-oncologic (brain and spine) cancers account for 19,000 new cases and 13,000 deaths per year. The early and proper diagnosis of these virulent cancers is critical to patient outcomes and diagnosis and treatment strategies are continually evolving. The multidisciplinary team that manages these patients involves medical and radiation oncology, neurosurgery, neuroimaging, nurses and therapists. Principles and Practices of Neuro-Oncology establishes a new gold standard in care through a comprehensive, multidisciplinary text covering all aspects of neuro-oncology. Six major sections cover all topics related to epidemiology and etiology, molecular biology, clinical features and supportive car...
Subjective cognitive decline (SCD) with self-reported concerns and mild cognitive impairment (MCI) are well-established to be at increased risk of developing Alzheimer’s disease (AD) dementia and a clinical continuum of dementia progression as a spectrum of AD. AD may develop from SCD to MCI (early MCI and late MCI) and eventually to AD. Nevertheless, until recently little was known about their pathophysiology associated with cognitive-behavioral syndrome. Although for researchers, scientists and clinicians, the pathophysiology of AD spectrum is an intriguing issue, delineating it in a clear way is far from easy. Taken together, in-depth understanding of neuroimaging-based pathology behind...
This manual, to be published in two volumes, provides a condensed overview of the analytical investigation of 80 Chinese Herbal Drugs which are most frequently in use. Thin layer chromatographic-, high pressure liquid chromatographic- and gas chromatographic-fingerprint analytical techniques allow the detection of all main low-molecular constituents of a plant drug and even single constituents can be visualized. Analytical results thereof are shown in numerous color figures. The quality proof of the investigation meets the standard of the European Drug Regulatory Authority. Furthermore, this volume gives a detailed description of the analytical methods used for several drugs. Bioactive constituents, pharmacological and biological activities of several single herbal drugs as well as their therapeutic applications are discussed.
The field of redox is rapidly changing, specifically in relation to plants where redox reactions are exacerbated compared to non-photosynthetic organisms. The development of proteomics has allowed the identification of hundreds of molecular targets of these systems, and the recent discovery of glutaredoxin's ability to bind iron sulfur centers (ISCs) and to participate in ISC assembly in other apoproteins has provided many new insights. This volume presents new research on oxidative stress in plants, ranging from the production of reactive oxygen species or reactive nitrogen species, to their accumulation, their involvement in signal transduction, and their degradation, while also covering the links among oxidative stress and biotic and abiotic stresses. - Cutting-edge reviews written from a broad range of scientific perspectives - For over 40 years, series has enjoyed a reputation for excellence - Contributors internationally recognized authorities in their respective fields
Clinical Otology is the complete reference for basic scientific information on the functioning of the ear and current techniques for the diagnosis, management, and rehabilitation of patients with common otologic disorders. In this edition the authors address important topics such as the genetic diagnosis of hereditary hearing loss, management of superior canal dehiscence, evidence-based management of otitis media with effusion, middle ear and brain stem implantable hearing devices, new applications of transtympanic therapy, and more. The book features the exquisite color photographs of world-class otologic photographer Eiji Yanagisawa, MD.Highlights of the third edition: New chapters on Mole...