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For many years, the immune and central nervous systems were thought to function independently with little or no interaction between the two. This view has und- gone dramatic changes over the past three decades. Indeed, we now know that there exists various feedback loops between the brain and immune systems that impact signi cantly upon different behavioral processes, including normal behavior and mental disorders. Pioneering efforts in generating this change were initiated by a number of early investigators. Included were those whose efforts were directed at establishing neuroimmune connections as well as others whose research focused upon the relationship between immunity, cytokines, and b...
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A comprehensive and authoritative review of the most important scientific and clinically relevant topics today in ligaments, tendons, and capsular biology, including their biomechanics and surgical reconstruction. The authors review the basic science of tendons in the hand and shoulder ligaments, the current clinical status of the shoulder and cruciate ligaments, and the latest advances in research on the healing of ligament and tendon to bone, artificial ligaments, and gene therapy. They also cover the major type 1 collagen soft tissues that are of particular interest to upper extremity surgeons and sports medicine specialists.
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Ronald J. Furlong of the United Kingdom per the short term with this method of biologic fixation formed the first clinical implantation of a hydroxy of total joint implants has withstood the test of time. apatite-coated (HA) hip implant in 1985, about 18 Our thanks are due to the authors of chapters in this volume for the effort they made to write and years ago. This was followed in 1986 by other HA submit their work to us in a timely fashion. These clinical implantations conducted by the ARTRO Group in France and Rudolf Geesink in the Nether authors, working in Europe, the United States, lands. Following these pioneers, many thousands of Japan, and Australia, do not all use English as their...