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Current Approaches to Therapy
The enormous impact of both clinical and basic research on the field of breast cancer can now be readily appreciated. It is the purpose of this new series of books to bring together the recent major advances in our understanding of the disease. The first volume is devoted exclusively to treatment. It is written by scholars who are actually investigating the biological principles which underlie our current approaches to therapy. For example, countless articles have appeared proposing some ad vantage for one surgical approach to primary breast cancer compared with another. The new message is that these arguments for the superior ity of one surgical approach over a.nother are valid only in that...
History of the Pancreas: Mysteries of a Hidden Organ
Never before has a comprehensive history of the pancreas like History of the Pancreas been published. It not only is a historical review of the science of medicine, it is liberally interspersed with anecdotal vignettes of the researchers who have worked on this organ. Much of it, such as the discovery of the duct of Wirsüng, of the islets of Langerhans, of insulin, gastrin and their tumors, reads like the adverture, which it is. This book, divided into 14 chapters, is written in a narrative style and is easily readable, as glimpses of the investigators, those who failed as well as those who succeeded, adds both perspective and human interest. Each chapter is completely referenced, totaling over 1500 references. As a reference book for students, teachers, investigators, writers, its detailed hjistorical documentation is unique. From the pre-Christian era of Asia Minor, to Greece, Rome, Europe and America, to the explosive progress in Japan, the history is there. History of the Pancreas: Mysteries of a Hidden Organ fills a gap.
DHEW Publication
None
Melanoma
Melanoma is the most life threatening form of skin cancer, the incidence of which has been rising in the developing world due to its link with sun exposure. The increase in incidence had made it imperative that clinicians managing these patients keep up-to-date with the latest advances, allowing them to provide optimal treatment. As with the other Challenges books, Challenges in Melanoma assumes a certain level of knowledge and builds on this by discussing only areas of controversy and uncertainty in the basic science and clinical management of the disease. Authors aim to provide a balanced answer based on the scientific evidence, but ultimately draw some conclusions that will be of relevance to clinical practice. The content is organised into three sections: aetiology; diagnosis, screening and prevention; and management. All the chapters ask practical and pertinent questions. The book takes a global view of melanoma as a public health risk as well as looking at management issues.
The Guild Handbook of Scientific Illustration
The Guild Handbook of Scientific Illustration, Second Edition Sponsored by the Guild of Natural Science Illustrators and written by top illustrators, scientists, and industry experts, The Guild Handbook of Scientific Illustration, Second Edition is an indispensable reference guide for anyone who produces, assigns, or simply appreciates scientific illustration. Offering broad coverage and more than 620 outstanding illustrations, this new edition offers up-to-date coverage on all aspects of this specialized field, from illustrating molecules and 3D modeling to important material and advice on copyright and contractual concerns, as well as establishing a freelance business. With step-by-step instructions, in-depth coverage of illustrative techniques and related tools, and helpful advice on the day-to-day business of scientific illustrating, it is easy to see why scientific illustrators refer to this book as their "bible."
Current Topics
Breast cancer continues to be a major problem. In Volume 1 of this series we dealt exclusively with topics concerned with therapy. In Volume 2 we explored various aspects of experimental biology which are critical to our developing better methods of diagnosis and treatment. In the pres ent volume, we tum to a series of individual topics of considerable interest, including systemic methods for hormonal ablation, screening for early cancer, male breast cancer, and more. The first chapter addresses the question of why some breast tumors metastasize and others do not. Based on elegant animal tumor models, Kim believes that metastasizing tumor cells are the undesirable by product of the host immune surveillance mechanism. Unstable mem brane structures lead to shedding of membrane constituents, abnormal locomotive properties, and evasion of the host defense system. Factors which alter membrane structure will therefore have to be considered in our approach to the management of early breast cancer.
Musculoskeletal Cancer Surgery
Steven A. Rosenberg, MD In the past two decades significant progress has quality of life. The use of local radiation therapy has occurred, in the management of patients with mus- had a profound impact on the ability to achieve local loskeletal cancers, that has improved both the survival control. Cooperation between surgeons and radiation and the quality of life of afflicted patients. Changes in therapists often results in the tailoring of surgical p- the management of these patients have mirrored cedures to maximize the combined application of these trends in the entire field of oncology. two effective treatment modalities. Although impact on The most significant change has been improvement...
Annual Report
None
Estrogen/antiestrogen Action and Breast Cancer Therapy
This book marks one of the achievements of the "Estrogen and Antiestrogen Action: Basic and Clinical Aspects" Wisconsin Clinical Cancer Center conference in June 1984. It is not intended to be a recount of the meeting proceedings but is, rather, a historical review of the development of this field of endeavor during the past 30 years. The chapters have been written by many of the leading experts in the field who were asked to recount the development of a particular area or laboratory idea in which they had been personally involved. The book is intended to provide both scientists and clinicians with a single-volume overview of both the basic principles of hormonal control of breast cancer and the recent clinical results from cooperative groups around the world.
