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Implications of Immune Landscape in Tumor Microenvironment
Tumor microenvironment (TME) plays an important role in immunosuppressive mechanisms that result in immune editing and treatment resistance. Elucidating the diversity of stromal and immune cell distribution, polarization, and changes in their gene expression signatures will enable a better understanding of key events to improve treatment and prognosis. With the onset of immune checkpoint inhibitors (ICIs) in clinics for patients with solid tumors and hematologic malignancies, immunotherapy has taken a new direction in cancer management, especially as combination therapies. However, limitations encountered with the use of ICIs, including toxicity and immune-related adverse events (irAE) indic...
The Melancholy of Anatomy
In The Melancholy of Anatomy, his ninth collection of poetry, Martin Corless-Smith turns his attention towards ageing and mortality, and in particular to the death of his father. Shifting between formal verse and prose, from the metaphysical to the whimsical, from surreal to anecdotal, the book moves between poetic articulations as a mind might through memories, sifting to find anything to hold on to as everything flows and falls away. At times melancholic at times nihilistic at times luminous and dark, this collection asks questions about poetry, memory and what it is to have loved and lived. Praise for The Fool and The Bee: "Corless-Smith has an extraordinary eye for detail and this meticu...
Catalog of Copyright Entries, Third Series
The record of each copyright registration listed in the Catalog includes a description of the work copyrighted and data relating to the copyright claim (the name of the copyright claimant as given in the application for registration, the copyright date, the copyright registration number, etc.).
Forlorn Light
To write these poems, I select a paragraph from a Woolf novel-The Waves or Mrs. Dalloway-and only use the words from that paragraph to create a poem. I essentially write poems while doing a word search using Virginia Woolf as source material. I don't allow myself to repeat words, add words, or edit the language for tense or any other consideration. These poems are simultaneously defined by both Woolf's choices with language as well as my own. They feel like an homage to this writer I so admire as well as a way of authentically expressing my lived experience.
Hyperborder
Roving vigilantes, fear-mongering politicians, hysterical pundits, and the looming shadow of a seven hundred-mile-long fence: the US–Mexican border is one of the most complex and dynamic areas on the planet today. Hyperborder provides the most nuanced portrait yet of this dynamic region. Author Fernando Romero presents a multidisciplinary perspective informed by interviews with numerous academics, researchers, and organizations. Provocatively designed in the style of other kinetic large-scale studies like Rem Koolhaas's Content and Bruce Mau’s Massive Change, Hyperborder is an exhaustively researched report from the front lines of the border debate.
