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Advances in Heterocyclic Chemistry
Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area--one of great importance to organic chemists, polymer chemists, and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.
Understanding Biological Emergencies
This book investigates the links between the main sources of biological emergencies and presents a comprehensive policy framework that seeks to achieve the ultimate goal of biological security. The work offers a new interdisciplinary approach to analyse the linkages between the three main sources of biological emergencies: intentional attacks, natural zoonotic transmission, and lab accidents. In doing so, the text describes the history of using nature to create a weapon, focusing on dispersal methods. The most important Select Agents for monitoring are described, with a special focus on anthrax and smallpox. The case studies presented include the use of the Biological Weapons Convention (BWC...
Comprehensive Medicinal Chemistry II
The first edition of Comprehensive Medicinal Chemistry was published in 1990 and was very well received. Comprehensive Medicinal Chemistry II is much more than a simple updating of the contents of the first edition. Completely revised and expanded, this new edition has been refocused to reflect the significant developments and changes over the past decade in genomics, proteomics, bioinformatics, combinatorial chemistry, high-throughput screening and pharmacology, and more. The content comprises the most up-to-date, authoritative and comprehensive reference text on contemporary medicinal chemistry and drug research, covering major therapeutic classes and targets, research strategy and organis...
Neurotoxicity of Halogenated Organic Compounds
Neurotoxicity of Halogenated Organic Compounds, Volume 10 covers three groups of Halogenated Organic Compounds (Chlorinated, Brominated, and Fluorinated Compounds) that are legacy and emerging contaminants, providing background information, characteristics, physicochemical properties, environmental contamination, and human exposure. Specific chapters covered in this release include Perspective on Halogenated Organic Compounds, The Neurotoxicity of Polychlorinated Biphenyls (PCBs), Neuroendocrine Effects of Polychlorinated Biphenyls (PCBs), Mechanisms of PCB Neurotoxicity: AHR and THR Dogma meet RYR reality, Microbiome and the Neurotoxicity of Brominated Flame Retardants (BFRs), and much more...
Progress in Heterocyclic Chemistry
Progress in Heterocyclic Chemistry Volume 5 deals critically with original material selected essentially from the 1992 heterocyclic literature. Chapters 1 and 2 are given over to reviews: in the first, SO2 extrusion from five-membered rings is discussed by R.A. Aitken and colleagues, which completes last year's review on this topic. The second review presents a review of 2-acylamino-3-dimethylaminopropenoates in heterocyclic synthesis. The chapters are arranged according to ring sizes as in the previous volumes and are supported by references, numerous diagrams and a subject index.
Research Advances of Tuberculosis Vaccine and its Implication on COVID-19
Tuberculosis (TB) is a global infectious disease caused by the Mycobacterium tuberculosis complex. The number of deaths caused by TB is second only to COVID-19. Therefore, vaccination plays an essential role in the prevention and control of TB. However, the efficacy of currently licensed TB vaccine, bacilli Calmette-Guérin (BCG), varies from 0%-80% in adults, and the protection only lasts for 10-15 years. Thus, there is an urgent need to develop advanced TB vaccines against TB infections.
4-Membered Heterocycle Synthesis
Four-Membered Heterocycle Synthesis offers a comprehensive approach to these unstable organic compounds, providing a systematic introduction to the synthesis and reactions of all common four-membered heterocycles and illustrating different methods to prepare specific four-membered heterocycles. Four-membered heterocyclic compounds are known as a class of unstable organic compounds because of their strain characteristics, which make them very beneficial as precursors for the formation of a broad range of complex heterocyclic molecules and for synthetic elaboration. - Provides a systematic introduction to the synthesis and reactions of all common four-membered heterocycles - Highlights different methods to prepare specific 4-membered heterocycles - Analyzes several types and families of compounds, with a large set of recent examples in the field
