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Some important constraints of anesthesia must be taken into consideration when the pharmacological properties of modern anesthetics are discussed. The most imp- tant of these could be that the target effect be achieved preferably within seconds, at most within a few minutes. Similarly, offset of drug action should be achieved within minutes rather hours. The target effects, such as unconsciousness, are pot- tially life-threatening, as are the side effects of modern anesthetics, such as respi- tory and cardiovascular depression. Finally, the patient’s purposeful responses are not available to guide drug dosage, because, either the patient is unconscious, or more problematically, the patient...
This book presents to all those who are interested in the history of Anaesthesiology historical details and information on the development of anaesthesiology in Germany and the remarkable growth of our Society. At the founding session of the German Society of Anaesthesia in Munich on 10 April 1953 42 persons had signed the founding documents. Today about 12,000 anaesthetists are members of the German Society of Anaesthesiology and Intensive Care Medicine, making the DGAI the biggest national society within ESA. Well known are the pioneering contributions of German scientists and surgeons to the development of general, regional and local anaesthesia during the 19th and the beginning of the 20th centuries. But less known outside Germany are the reasons for the delayed evolution of anaesthesiology as a specialty of its own in German medicine, far later than in the UK, Scandinavia or the USA. In this book you will find answers to this question and detailed information on the successful evolution of anaesthesiology especially at the Faculties of Medicine at German universities.
This new edition provides clinicians and trainees with the latest information on drugs in anaesthesiology. Presented in tabular format, each section covers a different drug category, explaining and comparing the properties and characteristics of drugs within that group. The second edition features and new chapter on pharmacological terms, and each chapter includes references for further reading. The comprehensive text is further enhanced by clinical images and figures. Key points Fully revised, new edition providing latest information on drug in anaesthesiology Presented in tabular format to allow easy comparison of similar drugs Second edition features a new chapter on pharmacological terms Previous edition (9788184484069) published in 2008
Die Deutsche Gesellschaft für Anästhesiologie und Intensivmedizin feiert im April 2003 ihr 50jähriges Bestehen. Dem Anlass gemäß veröffentlicht die DGAI eine Festschrift, in der u.a. die Entwicklung des Faches der Anästhesiologie beschrieben wird. Renommierte Vertreter und Wegbereiter beschreiben die Etablierung der Anästhesiologie in Deutschland, die Gründung der wissenschaftlichen Fachgesellschaften sowie die der Fachzeitschriften. Die ausführliche Darstellung der Geschichte der einzelnen Ordinariate runden das Werk ab.
Hardbound. International Congress Series 1168State of the Art Technology in Anesthesia and Intensive Care contains selected papers from the 18th International Symposium on Computing in Anesthesia and Intensive care held in Hamamatsu City, Japan. Four hundred participants from twenty-two countries focused their interest on promoting patient safety and quality improvement in anesthesia and intensive care using state of the art technology.The book also introduces eight new techniques for cardiac output estimation that encompasses almost all techniques available in the world.This is the only book presently available that compiles the most advanced technology in the field of anesthesia and intensive care medicine.
Der Autor untersucht in dieser Studie die spezifischen Wirkungen des neuen Pharmakons Propofol auf das zentrale Nervensystem durch pharmakokinetisch/-dynamische Modellbildung. Die Modellbildung soll den zeitlichen Verlauf der Wirkung in Abhängigkeit von den Blutspiegeln in ihrem nichtlinearen Zusammenhang bei verschiedenen Dosierungsstrategien beschreiben. Ziel der Untersuchung ist es, mit diesem Konzept die Grundlage für eine optimierte Anwendung von Propofol im Rahmen der totalen intravenösen Anästhesie zu schaffen. Gleichzeitig erfolgt damit die klinische Erprobung eines neuen Pharmakons, anders als sonst vielfach üblich, von Anfang an auf rationaler Ebene, die durch pharmakokinetische Modelle und pharmadynamische Daten gebildet wird. Somit wird ein auf Empirie beruhendes "trial and error"- Verfahren bei der Entwicklung von klinischen Dosierungsvorstellungen vermieden.
"Proceedings of the Second Edinburgh International Conference on Drug Absorption"--Pref.
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