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Human Cell Culture
Describes research technology for the growth and differentiation of all 12 types of the primary hematopoietic cells that develop into the various types of blood cells. Also provides background information, discusses current and future clinical applications of large-scale culture methods, and considers regulatory and ethical implications associated with using human and fetal tissues. The 13 studies include treatments of hematopoietic stem and progenitor cells, monocytes and macrophages, isolating and culturing human dendritic cells, purifying and culturing erythroid progenitor cells, the in vitro development of megakaryocytes and platelets, the mature polyclonal and antigen- specific cell expansion of T-lymphocytes, and in vitro T- lymphopoiesis. They are not indexed. Annotation copyrighted by Book News, Inc., Portland, OR
Human Cell Culture
The daily production of hundreds of billions of blood cells through the process of hematopoiesis is a remarkable feat of human physiology. Transport of oxygen to tissues, blood clotting, antibody- and cellular-mediated immunity, bone remodeling, and a host of other functions in the body are dependent on a properly functioning hematopoietic system. As a consequence, many pathological conditions are attributable to blood cell abnormalities, and a fair number of these are now clinically treatable as a direct result of hematopoietic research. Proliferation of hematopoietic stem cells, and their differentiation into the many different lineages of functional mature cells, is highly regulated and responsive to many environmental and physiological challenges. Our relatively advanced understanding of this stem cell system provides potentially important insights into the regulation of development in other tissues, many of which are now being acknowledged as stem ce- based, perhaps even into adulthood. The recent public and scientific fanfare following announcement of human embryonic stem cell studies suggests that stem cell research will continue to be a relevant and exciting topic.
Open
An award-winning journalist chronicles her first open relationship with “breathtaking honesty” (Los Angeles Times) in this “sexy, messy, necessary look at polyamory” (The Advocate). FINALIST FOR THE LAMBDA LITERARY AWARD • ONE OF THE BEST BOOKS OF THE YEAR: PopSugar, Them When Rachel Krantz met and fell for Adam, he told her that he was looking for a committed partnership—just one that did not include monogamy. Intrigued and more than a little nervous, Krantz decided to see whether their love could coexist with the freedom to date other people. Could they strike an exquisite balance between intimacy and independence, and find a way to feel passion for each other once the honeymoo...
The Implicit Function Theorem
The implicit function theorem is part of the bedrock of mathematical analysis and geometry. Finding its genesis in eighteenth century studies of real analytic functions and mechanics, the implicit and inverse function theorems have now blossomed into powerful tools in the theories of partial differential equations, differential geometry, and geometric analysis. There are many different forms of the implicit function theorem, including (i) the classical formulation for C^k functions, (ii) formulations in other function spaces, (iii) formulations for non- smooth functions, (iv) formulations for functions with degenerate Jacobian. Particularly powerful implicit function theorems, such as the Na...
Retirement Planning For Dummies
Advice and guidance on planning for retirement Retirement Planning For Dummies is a one-stop resource to get up to speed on the critical steps needed to ensure you spend your golden years living in the lap of luxury—or at least in the comfort of your own home. When attempting to plan for retirement, web searching alone can cause you more headaches than answers, leaving many to feel overwhelmed and defeated. This book takes the guesswork out of the subject and guides readers while they plan the largest financial obligation of their life. Take stock of your finances Proactively plan for your financial future Seek the help of professionals or go it alone Use online tools to make retirement planning easier Whether you're just starting out with a 401(k) or you’re a seasoned vet with retirement in your near future, this book helps younger and older generations alike how to plan their retirement.
Fundamental Analysis For Dummies
How to determine the true strength and stability of any business What's the key to multibillionaire Warren Buffett's five-decade run as the most successful investor in history? Fundamental analysis. Now, Fundamental Analysis For Dummies puts this tried and true method for gauging any company's true underlying value into sensible and handy step-by-step instructions.. In this easy-to-understand, practical, and savvy guide you'll discover why this powerful tool is particularly important to investors in times of economic downturn and how it helps you assess a business's overall financial performance by using historical and present data to forecast its future monetary value. You'll also learn how...
Management of Genetic Syndromes
The bestselling guide to the medical management of common genetic syndromes —now fully revised and expanded A review in the American Journal of Medical Genetics heralded the first edition of Management of Genetic Syndromes as an "unparalleled collection of knowledge." Since publication of the first edition, improvements in the molecular diagnostic testing of genetic conditions have greatly facilitated the identification of affected individuals. This thorough revision of the critically acclaimed bestseller offers original insights into the medical management of sixty common genetic syndromes seen in children and adults, and incorporates new research findings and the latest advances in diagn...
The Legal Profession
Sheldon Krantz begins The Legal Profession: What Is Wrong and How to Fix It by saying that the legal profession is in trouble, and should be. He then covers what is wrong by describing the current state of the legal profession, the emergence of BigLaw, the changing nature of law practice, and the access to justice crisis. This is followed up by addressing what needs to be done and setting forth a specific agenda to address its deficiencies: Make the legal profession more responsive to client and public service needs Resolve the access to justice crisis Involve law schools more directly in legal profession reform; and Create a new organization with a mandate to promote necessary changes in the legal profession on an ongoing basis He points out both promising developments as well the forces resisting change and identifies ways to overcome resistance to change and to transform the legal profession into the noble calling it should be.
Erythroid Cells
This series of books, devoted to aspects of blood cell biochemistry, development, immu nology, and ultrastructure, has evolved and separated from the long-established Plenum series Subcellular Biochemistry. It is the intention of these volumes to draw together related areas of investigation and to provide, in the fullness of time, complete coverage of this rapidly advancing important biomedical discipline. Both fundamental and medically applied topics, dealing with normal and pathological cells, will be included. This, the first volume of the series, contains a diverse collection of chapters, all of which relate to erythroid cells. The range of material included is extremely broad and the au...
Handbook of Growth Factors
Handbook of Growth Factors, Volume III is devoted to hematopoiesis and its regulation by endogenous factors with growth stimulatory and growth inhibitory properties. The book provides detailed discussions on signaling agents related to the regulation of hematopoiesis, including the interleukins, the colony-stimulating factors, the interferons, the tumor necrosis factors, the erythropoietic growth factors, the platelet-derived growth factor, the leukemia inhibitory factor, and the transferrins. The structure and function of each factor is covered in detail, as well as its receptor and postreceptor mechanism of action and its possible role in neoplastic processes. The book also explores the present state of the knowledge about megakaryocyte growth factors and macrophage-derived growth factors.
