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Vascular Surgery
A certain standardization has now been introduced into the operative techniques of vascular surgery after the stormy developments of the last few decades. It is to make the knowledge gained in those years more widely available that this operative manual Vascular Surgery has been compiled. It contains contributions from numerous authors at European centers of vascular surgery. Both the young surgeon in training and the more experienced surgeon continuing training will find in this book all the necessary instructions for the diagnosis, preoperative preparation, and reconstructive surgery of the arteries, veins, and lymph vessels (the coronary vessels are excluded from this book, as they are co...
Cancer Therapy
A variety of new cancer therapy modalities are discussed and evaluated in this book. It aims to demonstrate that the combination of classical chemo- and radiotherapy with new approaches in the field of immunotherapy can result in an improved treatment modality. Immunotherapy in this context consists of therapy with monoclonal antibodies, hematopoietic growth factors and other lymphokines. Results of early clinical trials with IL-2, GM-CSF and monoclonal antibodies against gastrointestinal tumors and melanoma are included. The progress in regional chemotherapy strategies, for example of the liver, is shown. In addition, the development of new chemotherapeutic agents with a different mode of action as well as better tolerability is presented. The use of hormones, such as LH-RH agonists, allows hormone-dependent tumors such as prostatic and breast cancer to be treated without strong adverse reactions. These recent findings give the reader insight into exciting therapeutic directions made possible by such combined, rather than single, modalities.
Regional Opioid Analgesia
by E.K. ZSIGMOND, M.D. Department of Anesthesiology University of Illinois Chicago U.S.A. It is, indeed, a distinct honor and privilege to be invited by the authors to write a preface to this monumental monograph, Regional Opioid Analgesia. Regional Opioid Analgesia is a colossal undertaking by Drs. De Castro, Meynadier and Zenz shortly after the introduction of this revolutionary approach to pain relief which opened a new epoch in analgesiology. This is, indeed, the first authentic and comprehensive textbook encompassing the current knowl edge on this novel approach to pain relief. We are indebted to the authors for introducing the new opioids to regional analgesia with the scientists, who ...
Cutaneous Melanoma and Precursor Lesions
In recent years much progress has been made in knowledge and understanding of the biology of cutaneous melanoma. In this respect etiological factors, prognostic factors, antigen expression of melanoma cells, immune response and mechanisms of metastasis formation have to be mentioned. It is the purpose of this book to give a review on fundamental aspects, diagnosis and prognosis, and treatment of cutaneous melanoma and precursor lesions. Moreover, previously unpublished new data are presented. A post-graduate Boerhaave course "Cutaneous Melanoma and Precursor Lesions" was held at Leiden University on 12 and 13 April,. 1984. The proceedings are contained in this volume. The editors would like ...
Thoracic Surgery in Children and Adolescents
The diagnosis and treatment of both congenital and acquired thoracic pathologies in children and adolescents require a high degree of specialization. This book provides practical guidelines for thoracic surgeons who operate on patients from neonatal age to adolescence and for pediatric surgeons who are challenged to treat disorders such as cystic malformations of the lung, mediastinal tumors, or chest wall deformities. The chapters, written by internationally acclaimed authors, include expert commentaries with tips and tricks for the clinical practice. Plus: QR codes for access to videos of surgical procedures.
Developing Insights in Cartilage Repair
This comprehensive book discusses cartilage repair and all its aspects. These aspects vary from basic insights in cartilage biology and regeneration via MRI, to results of existing cartilage repair techniques and upcoming novel approaches. Fundamental cartilage biology is the topic covered within the first chapters of the book. These chapters not only provide an insight in healthy, damaged and regenerative cartilage but also describe developments in gene therapy and methods to enhance chondrogenesis of stemcells and prevent hypertophic differentiation. There is a huge progress in the possibilities of MR imaging of both healthy, damaged and regenerative cartilage. These developments not only ...
Graft Preservation
Recently, solid organ transplant outcomes have benefited from improvements in graft preservation strategies. The use of ex vivo machine perfusion for organ has increased the donor pool and extended criteria for donor organs that would have previously been excluded from transplantation. Utilization of machine perfusion has protected donor organs from the injuries traditionally encountered by static cold storage, minimized rates of primary graft dysfunction, and even allowed for recovery of the function of marginal organs. Machine perfusion has also extended preservation periods well beyond what is considered acceptable after static cold storage for kidney, liver, lung, and hearts. The extende...
The Hippocampus
The hippocampus is an important brain region, a true central hub for memory of various kinds and other processes. Neuropsychiatric disorders such as Alzheimer's disease, drug addiction, and schizophrenia are characterized by hippocampal alterations. The dentate gyrus of the hippocampus is a site exhibiting adult neurogenesis. This book covers the topic of the hippocampus from various perspectives. It discusses adult neurogenesis, effect of enriched environments on hippocampal plasticity, and long-term potentiation-associated gene expression. The book also addresses multiscale representations of complex environments and strategies in the hippocampus-dependent spatial tasks. Finally, insight into the hippocampus as a link between negative affect and relapse to psychostimulants is provided. The book collects evidence of various hippocampal functions in healthy and disordered brain.
Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
