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Multi-Targeted Approach to Treatment of Cancer
In this book, clinicians and basic scientists from USA, India, and other countries discuss the rationales and clinical experiences with targeted approaches to treat, prevent, or manage cancer. Cancer is a hyperproliferative disorder that is regulated by multiple genes and multiple cell signaling pathways. Genomics, proteomics, and metabolomics have revealed that dysregulation of dozens of genes and their products occur in any given cell type that ultimately leads to cancer. These discoveries are providing unprecedented opportunities to tackle cancer by multi-faceted approaches that target these underpinnings. This book emphasizes a multi-targeted approach to treating cancer, the focus of the 5th International Conference on Translational Cancer Research that was held in Vigyan Bhawan, Delhi (India) from Feb 6-9, 2014.
Comprehensive Toxicology
An explosive increase in the knowledge of the effects of chemical and physical agents on biological systems has led to an increased understanding of normal cellular functions and the consequences of their perturbations. The 14-volume Second Edition of Comprehensive Toxicology has been revised and updated to reflect new advances in toxicology research, including content by some of the leading researchers in the field. It remains the premier resource for toxicologists in academia, medicine, and corporations. Comprehensive Toxicology Second Edition provides a unique organ-systems structure that allows the user to explore the toxic effects of various substances on each human system, aiding in providing diagnoses and proving essential in situations where the toxic substance is unknown but its effects on a system are obvious. Comprehensive Toxicology Second Edition is the most complete and valuable toxicology work available to researchers today. Contents updated and revised to reflect developments in toxicology research Organized with a unique organ-system approach Features full color throughout Available electronically on sciencedirect.com, as well as in a limited-edition print version
Bioactive Foods and Extracts
Though there is considerable historical and anecdotal record for the use and efficacy of the cancer preventative properties of vegetables, fruits, and herbs, modern healthcare professionals require scientific evidence and verifiable results to make defensible decisions on the benefits, risks, and value of botanicals and their extracts in the preven
When Strangers Meet…
What happens when Jai is stranded at the metro station with an irritating stranger called Iyer & a mysterious Pathan? How will the tale from Iyer’s past affect Jai’s future? And why does the mysterious Pathan keep staring at Jai? What happens inside that small room of the metro station? Nobody believes Jai when he claims that ‘He was there!’. People think he is crazy, but is he? The story revolves around Pathan, Jai & Iyer, and their tryst with each other’s destiny.A light-hearted drama with a heavy tint of suspense that captures father-son relationships from the viewpoints of three different strata of society. Action,Comedy, Romance, Drama, Suspense... A typical Bollywood fiction... A touching tale about choosing between the paths of our dreams and their expectations.
Curative and Preventive Properties of Medicinal Plants
This book provides scientific reports on the therapeutic potential of medicinal plants using animal models and provides information on the beneficial role of medicinal plants on human diseases. It looks at a number of medicinal plants and examines the medicinal properties and activities of the plants for a variety of health issues, such as for diabetes, cardiovascular disease, neurodegenerative disease, organ dysfunctions, cancer, labor and postpartum issues, and more. The therapeutic mechanisms of some phytoconstituents are also discussed.
Transmembrane Dynamics of Lipids
The first and only book devoted entirely to MEMBRANE LIPID ASYMMETRY AND ITS BIOLOGICAL IMPLICATIONS Transmembrane Dynamics of Lipids is comprised of contributions from expert authors from leading research groups that present up-to-date quantitative data on the formation, stability, and biological consequences of the asymmetrical organization of lipids in cell membranes. Incorporating an impressive amount of new, previously uncollected data, the book examines transmembrane asymmetry and movement of lipids in biological membranes, and methods for the measurement of transmembrane lipid motion, emphasizing the role of lipid flippases and discusses biological functions associated with lipid asym...
Anti-Inflammatory Drug Discovery
A comprehensive review of recent medicinal chemistry approaches to a variety of important therapeutic targets and a key reference for those interested in the prosecution of modern drug discovery programs directed at anti-inflammatory mechanisms of action.
Inflammation, Oxidative Stress, and Cancer
Increasing scientific evidence suggests that the majority of diseases including cancer are driven by oxidative stress and inflammation, attributed to environmental factors. These factors either drive genetic mutations or epigenetically modify expression of key regulatory genes. These changes can occur as early as gestational fetal development, and
Phyllanthus Species
The genus Phyllanthus has over 1,000 species distributed worldwide, many of which have been used indigenously for the treatment of a variety of ailments for generations. Researchers have developed ways to analyze the potential of these plants and demonstrated the pharmacological action and various chemical entities present in each of them. They have validated the folklore claims and used this knowledge to design cost-effective and reliable sources of medicine. The first book to exclusively examine the genus Phyllanthus, Phyllanthus Species: Scientific Evaluation and Medicinal Applications begins with a systematic classification and identification manual for various plants in the genus, follo...
Lipid Nanocarriers in Cancer Diagnosis and Therapy
Lipid Nanocarriers in Cancer Diagnosis and Therapy fills a need for an accurate, coherent and authoritative introduction to lipid nanocarriers focusing in cancer therapy; both because of the growing popularity of these modern drug delivery systems and also because of the emergent need of dealing with cancer treatment. This handbook deals with lipid nanocarriers for targeted delivery to tumours of various organs and combination of these with other methods of treatment of cancer such as radiotherapy, diagnostic and imaging analysis. Lipid nanocarriers are also used for gene therapy for cancer.
