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Urinary tract infections (UTIs) are among the most common bacterial infections in humans. Their frequency varies with age, gender and socioeconomic background. Authored by scientists especially selected for their expertise in the field, this book reviews the latest research data and presents current concepts of the pathogenesis, prevention and treatment of UTIs. Modern methods of diagnosis and new antibacterial agents are evaluated, and recommendations for the choice of antimicrobial and the duration of treatment in different conditions are provided. Besides acute cystitis and pyelonephritis, special attention is given to complicated UTIs, such as infections in renal transplant patients, pat...
All modern aspects of etiology, pathogenesis, diagnosis and therapy of prostatitis are critically evaluated in this book. Of special interest to the readers will be the modern diagnostic management of chronic prostatitis and the debatable therapeutic approach to chronic nonbacterial prostatitis.
Bridging the gap between medical and surgical specialties in critical care, Textbook of Critical Care, 8th Edition, offers a practical, multidisciplinary approach to the effective management of adult and pediatric patients in the ICU. An outstanding editorial team, led by world-renowned intensivist Dr. Jean-Louis Vincent, assisted by Dr. Frederick A. Moore and new editors Drs. Rinaldo Bellomo and John J. Marini, provides the evidence-based guidance you need to overcome a full range of practice challenges. A full-color art program, relevant basic science and key summary points in every chapter, and expert contributing authors from all over the world make this an indispensable resource for eve...
Urinary tract infections (UTIs) are among the most common bacterial infections worldwide, and they are also the leading cause of hospital-acquired infections. Therefore, the appropriate management of UTIs is a major medical and financial issue. This book covers different clinical manifestations of UTI, with special emphasis on some hard-to-treat diseases, and special conditions in respect of treatment; antibiotic resistance and the available alternative strategies for the prevention and treatment of UTIs and it deals with urinary tract infections in children. The aim of this book is to give a summary about the different aspects of the diagnosis, management and prevention of urinary tract infections for all medical disciplines.
In many fields, most notably medicine and molecular biology, the understanding of the structure and function of carbohydrates and glycoconjugates remains vital. This new volume contains critical reviews covering the latest findings in both chemical and biological sciences, and demonstrates the interdisciplinary nature of modern carbohydrate research. This book addresses diverse applications that continue to be major challenges for carbohydrate chemists. The book starts with a review of Gérard Descotes contribution to the field as a pioneer of French modern carbohydrate chemistry. Green nanocatalytic oxidation of free sugars, photosensitive glycomacrocycles, the application of disaccharides in supramolecular chemistry, recent advances in the radiation chemistry of polysaccharides, and the cell wall pectic rhamnogalacturonan II, an enigma in plant glycobiology are just some of the diverse topics presented in Volume 45. This set of reports will certainly benefit any researcher who wishes to learn about the latest developments in the carbohydrate field.
A working guide to the use of drugs in the treatment of urological disease The content is arranged so that the busy urologist can go quickly and easily to the relevant section Coverage of treatment is evidence-based It is the only current book on drug treatment in urology Great strides have been made in the understanding of the scientific basis of urological conditions and this has allowed the development of drugs for a wide variety of urological disorders. This book provides urologists with a working guide to the rapidly growing armoury of drugs available to them.
Antibacterial agents act against bacterial infection either by killing the bacterium or by arresting its growth. They do this by targeting bacterial DNA and its associated processes, attacking bacterial metabolic processes including protein synthesis, or interfering with bacterial cell wall synthesis and function. Antibacterial Agents is an essential guide to this important class of chemotherapeutic drugs. Compounds are organised according to their target, which helps the reader understand the mechanism of action of these drugs and how resistance can arise. The book uses an integrated “lab-to-clinic” approach which covers drug discovery, source or synthesis, mode of action, mechanisms of...
The quinolones are making a significant contribution to patient care and have added a new dimension to antibacterial therapy. During the last decade, they became important agents for treating hospital-acquired infections. This volume covers their mechanisms of action, resistance mechanisms and epidemiology, pharmacokinetics, safety and clinical applications. Their effectiveness for respiratory, urinary, sexually transmitted, skin, soft tissue, bone and joint infections, infections of the eyes, ears, nose and throat, and less common infections such as mycobacterial, Brucella and others are reviewed. Also described is their use in pediatric, oncology and immunocompromised patients. The quinolone story continues to be intriguing with exciting future implications.This monograph is an important comprehensive review and update for researchers and clinicians in pharmacology, clinical medicine, molecular and cell biology, epidemiology and the pharmaceutical industry.
The International Society of Chemotherapy meets every two years to review progress in chemotherapy of infections and of malignant disease. Each meeting gets larger to encompass the extension of chemotherapy into new areas. In some instances, expansion has been rapid, for example in cephalosporins, pen icillins and combination chemotherapy of cancer - in others slow, as in the field of parasitology. New problems of resistance and untoward effects arise; reduction of host toxicity without loss of antitumour activity by new substances occupies wide attention. The improved results with cancer chemotherapy, es pecially in leukaemias, are leading to a greater prevalence of severe infection in pati...