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Aus erster Hand berichten die Autoren der Beiträge dieses Bandes, mit welchen Strategien in der kommerziellen Forschung nach Wirkstoffen gegen Infektionskrankheiten gesucht wird. Dabei konzentrieren sie sich in erster Linie auf Parasitosen, berücksichtigen aber auch bakterielle Infektionen. Hochinteressante Informationen, die man in dieser Form nirgends findet!
Comprehensive Inorganic Chemistry II, Nine Volume Set reviews and examines topics of relevance to today’s inorganic chemists. Covering more interdisciplinary and high impact areas, Comprehensive Inorganic Chemistry II includes biological inorganic chemistry, solid state chemistry, materials chemistry, and nanoscience. The work is designed to follow on, with a different viewpoint and format, from our 1973 work, Comprehensive Inorganic Chemistry, edited by Bailar, Emeléus, Nyholm, and Trotman-Dickenson, which has received over 2,000 citations. The new work will also complement other recent Elsevier works in this area, Comprehensive Coordination Chemistry and Comprehensive Organometallic Che...
This volume presents select papers presented at the 7th International Conference on Recent Advances in Geotechnical Earthquake Engineering and Soil Dynamics. The papers discuss advances in the fields of soil dynamics and geotechnical earthquake engineering. Some of the themes include slope stability, shallow and deep foundations, geosynthetics, ground improvement techniques, etc. A strong emphasis is placed on connecting academic research and field practice, with many examples, case studies, best practices, and discussions on performance based design. This volume will be of interest to researchers and practicing engineers alike.
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Perinatal Programming addresses the environment-dependent setting of fundamental life functions and dispositions for diseases in developmental periods during pregnancy and in early infancy. It provides a new view of the origins of health and diseases. To realize these associations may enable us to prevent diseases for the long term. This book reviews actual state-of-the-art knowledge in the perinatal programming field. The authors are internationally known scientists of this research area.
This book collects 5 keynote and 15 topic lectures presented at the 2nd European Conference on Earthquake Engineering and Seismology (2ECEES), held in Istanbul, Turkey, from August 24 to 29, 2014. The conference was organized by the Turkish Earthquake Foundation - Earthquake Engineering Committee and Prime Ministry, Disaster and Emergency Management Presidency under the auspices of the European Association for Earthquake Engineering (EAEE) and European Seismological Commission (ESC). The book’s twenty state-of-the-art papers were written by the most prominent researchers in Europe and address a comprehensive collection of topics on earthquake engineering, as well as interdisciplinary subje...
Vascular Smooth Muscle: Metabolic, Ionic, and Contractile Mechanisms addresses the vascular smooth muscle function by describing plasma lipoprotein structure, synthesis, and transport in relation to the concepts of altered vascular smooth muscle lipid metabolism leading to the genesis of atherosclerotic disease. This book is organized into six chapters and begins with an introduction to the complexities of energy metabolism and how metabolic events can be correlated with a simultaneous quantitative assessment of smooth muscle mechanics and the contractile machinery at the molecular level. The next two chapters offer the reader a view of smooth muscle membrane properties in terms of the distr...
There are now compelling human epidemiological and animal experimental data that indicate the risk of developing adult-onset complex diseases and neurological disorders are influenced by persistent epigenetic adaptations in response to prenatal and early postnatal exposures to environmental factors. Epigenetics refers to heritable changes in gene function that occur without a change in the sequence of the DNA. The main components of the epigenetic code are DNA methylation, histone modifications, and non-coding RNAs. The epigenetic programs are established as stem cell differentiate during embryogenesis, and they are normally faithfully reproduced during mitosis. Moreover, they can also be ma...
Although first reported in 1973, immune heparin-induced thrombocytopenia (HIT) remains one of the most frequent and devastating adverse drug reactions encountered by physicians. This thoroughly updated fifth edition from international experts Professors Warkentin and Greinacher is the gold standard for accurate diagnosis and management of this cond