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Interest in the biological effects of ionising radiation closely followed the identification of such radiation. The realisation that DNA is the site of genetic infonnation in cells subsequently focussed attention on DNA as an important target in the lethal and mutagenic effects of ionising radiation. Thus radiation effects upon DNA became an important area for fundamental scientific studies by radiation biologists, chemists and physicists. To a first approximation, the concerns of the three disciplines can be divided by time scales: the physical process of energy deposition from photon or charged 16 12 particle and subsequent relaxation (-10- to 10- secs), followed by chemical 12 2 reactions...
Includes section, "Recent book acquisitions" (varies: Recent United States publications) formerly published separately by the U.S. Army Medical Library.
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
How to implement effective event-processing solutions Business people and IT professionals understand well the benefits of corporate agility and fast response to emerging threats and opportunities. However, many people are less familiar with the techniques now available to help accomplish those aspirations. Event processing has emerged as the key enabler for situation awareness and a set of guiding principles for systems that can adapt quickly to shifts in company and market conditions. Written by experts in the field, this prescriptive guide explains how to use event processing in the design of business processes and the systems that support them. Event Processing: Designing IT Systems for Agile Companies covers: The role of event processing in enabling business dashboards and situation awareness Types of event-processing applications and their costs and benefits How event-driven architecture (EDA) complements conventional request-driven SOA How to implement event processing without disrupting existing applications
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A critical evaluation of the state of understanding of the principles of tribology and its ability to serve the practical and commercial needs of this technology generally, particularly in the context of composite systems.
The free-radical chemistry of DNA had been discussed in some detail in 1987 in my book The Chemical Basis of Radiation Biology. Obviously, the more recent developments and the concomitant higher level of understanding of mechanistic details are missing. Moreover, in the living cell, free-radical DNA damage is not only induced by ionizing radiation, but free-radical-induced DNA damage is a much more general phenomenon. It was, therefore, felt that it is now timely to review our present knowledge of free-radical-induced DNA damage induced by all conceivable free-radical-generating sources. Originally, it had been thought to include also a very important aspect, the repair of DNA damage by the ...