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With reference to Indian parliament and state legislatures.
Progress in Medicinal Chemistry provides a review of eclectic developments in medicinal chemistry. This volume continues in the serial's tradition of providing an insight into the skills required of the modern medicinal chemist; in particular, the use of an appropriate selection of the wide range of tools now available to solve key scientific problems. - Progress in Medicinal Chemistry provides a review of eclectic developments in medicinal chemistry
What is democracy? Under what conditions does it thrive? What are the consequences of democracy? This book aims to answer these questions and more by exploring different varieties of democracies around the world. It starts with definitions of democracy and then divides the concept into three dimensions, which provide a framework for the study of democracy in all its forms. These dimensions form the three main sections of the book: *constitutional democracy which explores political rights *participatory democracy which focuses on participation of citizens *egalitarian democracy which examines outcomes of democracy in terms of equality. Democracy concludes by surveying the findings of this empirical study and a discussion on the meanings and consequences of democracy in a globalizing world.
Lynch syndrome (LS) is the most common cause of inherited colorectal cancer, a disease with a high mortality rate. An estimated 37,000 of diagnosed colorectal cancer cases worldwide are attributed to Lynch syndrome each year. Intensive cancer screening, with early initiation and frequent follow-up, can reduce colorectal cancer incidence and mortality in LS patients. This book provides an up-to-date overview on the genetic and epigenetic basis of Lynch syndrome. It evaluates clinical features of the disease and critically comments on molecular tools available for identifying mutations responsible for Lynch syndrome; in addition the importance of functional assays that can help clarify the clinical nature of identified mutations is also discussed. The book also focuses on challenges in genetic counselling of at-risk individuals and discusses related ethical issues. The purpose of the book is to give a concise knowledge base for the broader scientific and medical community, including genetic counselors, in order to improve awareness on the potential impact that the diagnosis of LS has on treatment, management and surveillance of LS patients.
Table of contents
Progress in Medicinal Chemistry provides a review of eclectic developments in medicinal chemistry. This volume continues in the serial's tradition of providing an insight into the skills required of the modern medicinal chemist; in particular, the use of an appropriate selection of the wide range of tools now available to solve key scientific problems. Progress in Medicinal Chemistry provides a review of eclectic developments in medicinal chemistry
This book provides a state-of-the-art approach to the molecular basis of hematologic diseases and its translation into improved diagnostics and novel therapeutic strategies. Several representative hemato-oncologic malignancies are analyzed in detail: acute lymphoblastic leukemia, acute myeloid leukemia, B-cell Non-Hodgkin lymphomas, multiple myeloma, chronic lymphocytic leukemia, chronic myeloid leukemia, myelodysplastic syndromes, and myeloproliferative neoplasms. Experts in the field describe the molecular methods applied for modern diagnostics and therapies, such as hematopoietic stem cell transplantation, donor recipient matching, banking of biological material, analyses of post-transplant chimerism, and minimal residual disease monitoring. The volume concludes with an extensive section comprising thorough step-by-step protocols of molecular techniques in hematology, all of them validated in the authors’ own laboratories.
The exploding field of epigenetics is challenging the dogma of traditional Mendelian inheritance. Epigenetics plays an important role in shaping who we are and contributes to our prospects of health and disease. While early epigenetic research focused on plant and animal models and in vitro experiments, population-based epidemiologic studies increasingly incorporate epigenetic components. The relevance of epigenetic marks, such as DNA methylation, genomic imprinting, and histone modification for disease causation has yet to be fully explored.This book covers the basic concepts of epigenetic epidemiology, discusses challenges in study design, analysis, and interpretation, epigenetic laborator...
Despite the existence of a wide range of human rights instruments and procedures, human rights violations still abound. The authors of this book address this so-called human rights deficit, and the possible responses to it, from various disciplinary angles and mostly in the context of development. They explore the reasons for the continuation of economic, social and/or political exclusion and human rights violations at large. They also present keys for redressing the human rights deficit. The role of law, and questions of universality, inclusion and exclusion are central themes in this book. The need to take up civil and political rights and economic social and cultural rights on equal footing is recognized by several of the authors, and so is that of bridging the public-private divide. Specific contributions address among others the importance of human rights training and education, the role of NGO's in a globalizing world, minorities, gender and women's rights, accountability of multinational corporations, and the problem of human trafficking.
Papers presented at the three day International Conference on "Changing Global Profile of Japanese Studies : Trends and Prospects", held at New Delhi during 6-8 March 2009.