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The mechanisms underlying acute and chronic lung diseases are complex, reflecting the interplay between multiple cell types, their microenvironment and exogenous challenges. While traditional in vitro cell culture approaches have been instrumental in advancing our knowledge of cellular signalling and function, they typically lack the cell-cell and cell-matrix interactions that define the niche in which lung cell and tissue functions emerge. Implementing in vivo and ex vivo three-dimensional (3D) models more realistically mimicking the in vivo cell-extracellular matrix (ECM) crosstalk should facilitate a considerable leap towards better understanding lung diseases and thus in investigating ne...
Directory of foreign diplomatic officers in Washington.
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Where did your surname come from? Do you know how many people in the United States share it? What does it tell you about your lineage? From the editor of the highly acclaimed Dictionary of Surnames comes the most extensive compilation of surnames in America. The result of 10 years of research and 30 consulting editors, this massive undertaking documents 70,000 surnames of Americans across the country. A reference source like no other, it surveys each surname giving its meaning, nationality, alternate spellings, common forenames associated with it, and the frequency of each surname and forename. The Dictionary of American Family Names is a fascinating journey throughout the multicultural United States, offering a detailed look at the meaning and frequency of surnames throughout the country. For students studying family genealogy, others interested in finding out more about their own lineage, or lexicographers, the Dictionary is an ideal place to begin research.
In January 2002, the Egyptian Ministry of Culture ran a competition for an innovative design for a new Grand Museum of Egypt. This two-volume publication contains sketches, plans, elevations and computer models of the prize-winning design and all other second-phase entries.