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Volume 3 of Bioreaction Engineering covers the general principles and techniques of bioprocess monitoring and their application for various bioprocesses. Methods based on the author's long standing experience working with various bioprocesses are applied within the book. In particular, the cultivation of Baker's yeast; production of fusion protein with recombinant E. Coli, alkaline serine protease production with Bacillus licheniformis; production of penicillin V with Penicillin chrysogenum; Cephalosporin C with Acremonium chrysogenum and tetracycline with Streptomyces aureofaciens are considered. This book deals with the monitoring of batch and perfusion cultivations of animal cells and pro...
Alongside presenting the fundamentals, this book reviews the state of the art of mathematical modeling and control of bioprocesses, while demonstrating the application in various biological systems important to industry. At the same time, the application of different types of models and control strategies are illustrated, taking into account the recent developments in reactor modeling. In addition to modeling and control, the metabolic flux analysis and the metabolic design and their application to bioprocesses are considered.
A history of of the industrial ecosystem that focuses on the biological sewage treatment plant as an early example. Biological sewage treatment, like electricity, power generation, telephones, and mass transit, has been a key technology and a major part of the urban infrastructure since the late nineteenth century. But sewage treatment plants are not only a ubiquitous component of the modern city, they are also ecosystems--a hybrid variety that incorporates elements of both nature and industry and embodies multiple contradictions. In Hybrid Nature, Daniel Schneider offers an environmental history of the biological sewage treatment plant in the United States and England, viewing it as an earl...
Wissenschaftler aus Forschung und Praxis geben einen aktuellen und umfassenden Überblick in und über alle an der Biotechnologie beteiligten Fachdisziplinen. Die verfahrenstechnischen Vorgänge und ihre Grundlagen werden beschrieben. Die 4. Auflage des Werkes ist in jeder Hinsicht neu bearbeitet und um die Darstellung wichtiger Gebiete ergänzt.
Biotechnology has been labelled as one of the key technologies of the last two decades of the 20th Century, offering boundless solutions to problems ranging from food and agricultural production to pharmaceutical and medical applications, as well as environmental and bioremediation problems. Biological processes, however, are complex and the prevailing mechanisms are either unknown or poorly understood. This means that adequate techniques for data acquisition and analysis, leading to appropriate modeling and simulation packages that can be superimposed on the engineering principles, need to be routine tools for future biotechnologists. The present volume presents a masterly summary of the most recent work in the field, covering: instrumentation systems; enzyme technology; environmental biotechnology; food applications; and metabolic engineering.
Describes the state-of-the-art techniques and methods involved in the design, operation, preparation and containment of bioreactor systems, taking into account the interrelated effects of variables associated with both upstream and downstream stages of the design process. The importance of the initial steps in the development of a bioprocess, such as strain and media selection, that have an overwhelming influence on all further operations, is emphasized.;This work is intended for biochemical, chemical and bioprocess engineers; biotechnologists; industrial biochemists; micro- and molecular biologists; food scientists; and upper-level undergraduate and graduate students in these disciplines.
First multi-year cumulation covers six years: 1965-70.