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Axons and Brain Architecture
Several excellent monographs exist which deal with axons. These, however, focus either on the cellular and molecular biology of axons proper or on network organization of connections, the latter with only an incidental or abstract reference to axons per se. Still relatively neglected, however, is the middle ground of terminations and trajectories of single axons in the mammalian central nervous system. This middle level of connectivity, between networks on the one hand and local, in vitro investigations on the other, is to some extent represented by retrograde tracer studies and labeled neurons, but there have so far been many fewer of the complementary anterograde studies, with total visual...
The Primate Visual System
The last 20 years of research have been marked by exceptional progress in understanding the organization and functions of the primate visual system. This understanding has been based on the wide application of traditional and newly emerging methods for identifying the functionally significant subdivisions of the system, their interconnections, the
Cortical NO interneurons from embryogenesis to functions
Neuronal processing and physiology rely on a delicate interplay between glutamatergic excitatory neurons and GABAergic inhibitory interneurons in a spatially, temporally and cell-type specific manner. Understanding these processes is complicated further by the large diversity characterizing the cerebral cortex. Although recent advances have significantly improved our knowledge of its neuronal types, the identity and the roles of several subpopulations of GABAergic interneurons remain elusive. Presumably, because of their apparent paucity, their diversity, the highly labile nature of nitric oxide (NO) as well as its pleiotropic actions, the functional importance of NO-producing GABAergic interneurons is particularly enigmatic. This Research Topic will cover the different aspects of cortical NO interneurons, from their diversity, embryonic origins to their functions in the cortical circuit and physiology.
The Evolutionary Roots of Human Brain Diseases
"Traditionally, studies and textbooks in Neurology or Psychiatry, as well as allied disciplines, deal with proximate causes of diseases and therapies, but remain mute or minimally interested in their ultimate causes including the phylogeny and adaptive significance of disease manifestations. Yet, as clinicians or basic researchers, we are conscious of potential evolutionary roots of neurological and psychiatric symptoms, often offering a rudimentary explanation but never delving deeply into the current role of evolutionary science as it relates to health and disease. We may miss appreciation of the role of adaptive properties, evolutionarily based neuronal circuitries, unbalanced cellular en...
The Temporal Mind
Memories, sensory experiences, expectations, and intentions, as well as thoughts, fears, and hopes: all share a fundamental trait, the fact that our conscious psychological states take place in time, and often are about time in some way or other. Temporality is an inescapable feature of the mind which has preoccupied philosophers and psychologists in diverse traditions such as Locke, Hume, Reid, Kant, Helmholtz, James, Husserl, Broad, and Bergson. The Temporal Mind: A Philosophical Introduction is the first book to offer a detailed critical survey of recent work on the perception of time and the temporal features of the mind. Philippe Chuard introduces some of the central topics in contempor...
Another Day in the Monkey's Brain
ANOTHER DAY IN THE MONKEY'S BRAIN charts a neuroscientist's journey to understand the central mysteries of consciousness. Dr. Siegel began his career in the neurophysiology of vision in the 1980s, just when the field was coming into focus with the advent of new computing and imaging technologies. As a pioneer in the technique of mesoscopic imaging, he worked with some of the giants in vision science: Torsten Wiesel, Francis Crick, Tom Albright and many others. With insight and clarity, he shows how science is built on such relationships. Along the way, he gives a vivid sense of the abundant passion and creativity that drive scientists in their pursuit of understanding. From monkey to man, Dr. Siegel finds the beauty in the scientific discovery of self in mind and brain.
Wildlife Review
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