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This book is a useful guide for students, physicians in continuing education and practitioners who want to keep abreast of the latest developments in rheumatology. The chapters on the pathogenesis of rheumatoid arthritis and the biochemistry of inflammation present the latest research results in this field and are illustrated by a wealth of charts and tables. There follows practical and critical information on all drug groups that are currently used in the treatment of inflammatory rheumatic diseases and osteoarthritis. (Midwest).
First multi-year cumulation covers six years: 1965-70.
The International Symposium on Prostaglandins and Related Compounds, first held in Vienna 1972, revisited the city after 24 years for the 10TH Symposium. For the many re searchers working in this multi-disciplinary field it was an opportunity to exchange their ex periences and share new data with colleagues from all around the world. This scientific exchange was largely encouraged by the unseasonably cold and rainy weather. For the first time, there was quite a large attendance from the former Communist countries. Eugene Garfield prepared a key note address delivered during the meeting (The Sci entist 1996, 12) reviewing the contribution of the Nobel Laureates U.S. von Euler, l.R. Vane, S.K....
Perspectives on Anti-Inflammatory Drugs Inflammation is a very complicated process of interrelated events and cas cades that does not allow for an easily defined, focused attack for drug discovery. It is evident from years of research and development that certain classes of compounds (e.g., NSAIDs, steroids, and so on) have had a meas ure of success in alleviating pain and even dampening cellularlhormonal mechanisms involved in the process. Clear, mechanism-related therapies (e.g., for arthritis) and targeted drugs (e.g., for transplantation) have not been available in the past and, in reality, research in inflammation has re lied on more phenomenological approaches for resolving symptoms or on blatant cytoreductive approaches in cases like organ transplantation. In the last decade, approaches that have revealed novel cellular pathways in which intervention is possible for lymphocyte regulation (for example, cyclosporine and FK506) and small molecular weight mediators (e.g., leu kotriene inhibitors) are now either standard therapy or will be in a short time. These latter approaches have been the result of research from the 1970s up to the present.
Companies focus on maximizing short-term shareholder value, but that approach causes frequent economic crises that damage society. Economist Heinrich Anker argues that we should be working toward coevolutionor being of service to each otherwhich would promote growth for customers, employees, businesses, and society. One way companies can do this is by focusing on shared value, which is a concept that would give them a competitive advantage by linking business activities with a service to society. The Value Balance in Business approach is a way for firms of all sizes and ownership structures to succeed. Learn how the approach works, and get proven strategies to help employees find more meaning in their everyday work. By restoring the spiritual dimension to economics and everyday business, youll be taking an important step into not just making business more profitable, but it will make a difference. Embark on a road that leads to lasting prosperity for businesses, employees, and customers by creating shared value and becoming Wealthier Together.
A conceptual and cultural history of fever, a universally experienced and sometimes feared symptom. Winner of the CHOICE Outstanding Academic Title of the Choice ACRL Christopher Hamlin’s magisterial work engages a common experience—fever—in all its varieties and meanings. Reviewing the representations of that condition from ancient times to the present, More Than Hot is a history of the world through the lens of fever. The book deals with the expression of fever, with the efforts of medical scientists to classify it, and with fever’s changing social, cultural, and political significance. Long before there were thermometers to measure it, people recognized fever as a dangerous, if tr...
As a palliative medicine physician, you struggle every day to make your patients as comfortable as possible in the face of physically and psychologically devastating circumstances. This new reference equips you with all of today's best international approaches for meeting these complex and multifaceted challenges. In print and online, it brings you the world's most comprehensive, state-of-the-art coverage of your field. You'll find the answers to the most difficult questions you face every day...so you can provide every patient with the relief they need. Equips you to provide today's most effective palliation for terminal malignant diseases • end-stage renal, cardiovascular, respiratory, a...
This is the second edition of the widely praised book by Drs Eduardo D. Bruera and Russell K. Portenoy on all aspects of cancer pain.
This comprehensive reference work, updated from the first edition, brings together the knowledge and expertise of contributors from around the world. It includes new topics such as prostaglandin synthetase enzyme, new synthetic eicosanoids, innovative analytical methods, the influence of cytokines in the regulation of synthesis and actions, newer eicosanoids that influence the cardiovascular system, and newly discovered roles in reproduction and interactions with nitric oxide. This book satisfies a surge of interest in prostaglandins—NSAIDS (e.g. aspirin) are the biggest selling drugs of all time, and the field has been refreshed by the advent of new types (selective COX-2 inhibitors, anti-leukotiene drugs).