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Modifying Our Genes
  • Language: en
  • Pages: 101

Modifying Our Genes

  • Type: Book
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  • Published: 2021-03-31
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  • Publisher: SCM Press

If our bodies could do more things, would our lives be better? Genome editing is a rapidly developing technology that can modify human genes. It can cure heritable diseases, but we could even make certain genetic “improvements” to healthy people. Should we change human embryos genetically to achieve such goals? Bringing together a leading molecular biologist and a Christian ethicist this book responds to the need for solid information and helpful orientation for a pressing moral issue. They explain relevant technical issues without the jargon, clarify the most important philosophical and religious arguments and bring empirical insights to the question of what helps us lead meaningful lives.

Glycoanalysis Protocols
  • Language: en
  • Pages: 263

Glycoanalysis Protocols

Now fully updated and considerably expanded, Glycoanalysis Protocols, 2nd ed., makes available to all protein scientists, and particularly those working with today's pharmaceuticals, the most advanced and reproducible glycoanalysis techniques currently in use. Developed by highly experienced carbohydrate chemists, biochemists, and physical chemists, these detailed, up-to-date, and proven analytical techniques cover the areas of glycoprotein macromolecular structural analysis, oligosaccharide profiling, lipid conjugate characterization, microorganism structure determination, and proteoglycan function. Special attention has been given to advanced analytical techniques in biotechnology during the production of recombinant glycoproteins and other therapeutics. Hailed as "indispensable" in its first edition, Glycoanalysis Protocols, 2nd ed., continues with vital, time-tested techniques addressing the needs of both biomedical researchers and protein macromolecular structural chemists. It will well serve all those starting work on the analysis of glycoproteins, as well as more experienced investigators seeking to augment their expertise.

Forensic DNA Profiling Protocols
  • Language: en
  • Pages: 617

Forensic DNA Profiling Protocols

This state-of-the-art collection of easily reproducible methods includes all of the major techniques of DNA analysis currently used in forensic identity testing. The methods include the recovery of DNA from a large range of sample types, analysis of DNA as single and multi-locus VNTR probes, PCR amplification of STR and other loci, and mitochondrial sequencing. The expert scientists writing here -- many from laboratories around the world -- also discuss how to interpret the results in cases of unknown identity and disputed parentage.-- Covers all steps from extraction of human DNA through to analysis and interpretation-- Takes advantage of new methodologies such as capillary electrophoresis-- Clear step-by-step instructions ensure unfailing reproducibility.

Plant Virology Protocols
  • Language: en
  • Pages: 557

Plant Virology Protocols

The aim of Plant Virology Protocols is to provide a source of infor- tion to guide the reader through the wide range of methods involved in gen- ating transgenic plants that are resistant to plant viruses. To this end, we have commissioned a wide-ranging list of chapters that will cover the methods required for: plant virus isolation; RNA extraction; cloning coat p- tein genes; introduction of the coat protein gene into the plant genome; and testing transgenic plants for resistance. The book then moves on to treatments of the mechanisms of resistance, the problems encountered with field testing, and key ethical issues surrounding transgenic technology. Although Plant Virology Protocols deals with the cloning and expression of the coat protein gene, the techniques described can be equally applied to other viral genes and nucleotide sequences, many of which have also been shown to afford protection when introduced into plants. The coat protein has, however, been the most widely applied, and as such has been selected to illustrate the techniques involved. Plant Virology Protocols has been divided into six major sections, c- taining 55 chapters in total.

Stress Response
  • Language: en
  • Pages: 480

Stress Response

Mammalian cells have evolved a complex multicomponent machinery that enables them to sense and respond to a wide variety of potentially toxic agents present in their environment. These stress responses are often associated with an increased cellular capacity to tolerate normally lethal levels of an insult. The realization that the mammalian stress response may be intimately linked with many human diseases, including rheumatoid arthritis, ischemia, fever, infection, and cancer, has led to an explosion of interest in this research area. Stress Response: Methods and Protocols brings together a diverse array of practical methodologies that may be employed to address various aspects of the respon...

Natural Killer Cell Protocols
  • Language: en
  • Pages: 394

Natural Killer Cell Protocols

In Natural Killer Cell Protocols: Cellular and Molecular Methods, Kerry S. Campbell and Marco Colonna have assembled a comprehensive collection of readily reproducible methods designed to study natural killer (NK) cells from the broadest variety of viewpoints. These include not only classic techniques, but also new approaches to standard methods, newly evolved techniques that have become valuable for specific applications, and unique models for manipulating and studying NK cells. Among the advanced methods covered are those for in vitro transendothelial migration, in vivo detection of cells migrating into tumors, immunofluorescence staining of intracellular cytokines, and in vitro NK cell de...

The Handbook of Financing Growth
  • Language: en
  • Pages: 514

The Handbook of Financing Growth

An in-depth look at the strategies, capital structure, and fund raising techniques for emerging growth and middle-market companies. Here is a comprehensive and practical guide to understanding and applying the basics of corporate finance to emerging growth and middle-market companies. Using empirical data and actual company cases to illustrate capital structures and financing approaches, the book provides a detailed discussion of the many funding instruments, from traditional bank loans and asset-based financing to different types of private equity and other creative solutions; the types of funding sources and their expected rates of returns; and typical deal terms.

History of the University of Connecticut School of Business Administration
  • Language: en
  • Pages: 242

History of the University of Connecticut School of Business Administration

The School of Business Administration at the University of Connecticut was created in 1940 at about the same time that the university changed its name to the University of Connecticut. This book chronicles the School’s journey to excellence over its first 75 years of existence. The School operates degree programs at four major locations. The School has grown from a faculty of 5 in 1940 to 112 in 2015. Starting with just an undergraduate program in 1940 the offerings of the school now include multiple MBA and MS programs as well as a Ph.D. program. Recognition of the quality of the School’s programs is represented by its AACSB accreditation and its rankings. In the most recent year its MBA program has been ranked in the Top 50 among all programs and the Top 25 among all public programs. Its MS in Accounting Program recently was ranked as number 3 in the country.

AACR 2022 Proceedings: Part B April 11-13
  • Language: en
  • Pages: 3709

AACR 2022 Proceedings: Part B April 11-13

The AACR Annual Meeting is the focal point of the cancer research community, where scientists, clinicians, other health care professionals, survivors, patients, and advocates gather to share the latest advances in cancer science and medicine. From population science and prevention; to cancer biology, translational, and clinical studies; to survivorship and advocacy; the AACR Annual Meeting highlights the work of the best minds in cancer research from institutions all over the world.

AACR 2019 Proceedings: Abstracts 1-2748
  • Language: en
  • Pages: 2881

AACR 2019 Proceedings: Abstracts 1-2748

American Association for Cancer Research 2019 Proceedings: Abstracts 1-2748 - Part A