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Type 1 diabetes (TD1) is one of the most common endocrine disorders in children and can occur at any age. Incidences of T1D have steadily increased worldwide, and it is largely considered an autoimmune disorder resulting from the specific destruction of pancreatic beta-cells producing insulin. However, T1D pathophysiology is still not completely understood, and although insulin and other therapies ameliorate the manifestations of the disease, no cure is currently available. This book has been written by widely acknowledged experts, with each chapter providing unique information on emerging aspects of T1D. Because a large body of information has been available regarding T1D, this book highlights lesser explored topics linked to the subject using important and recent knowledge that presages directions for further research. Current possibilities to forestall diabetic complications are also explored.
Erectile dysfunction is a widespread problem, affecting many men across all age groups and it is more than a serious quality of life problem for sexually active men. This book contains chapters written by widely acknowledged experts, each of which provides a unique synthesis of information on emergent aspects of ED. All chapters take into account not only the new perspectives on ED but also recent extensions of basic knowledge that presage directions for further research. The approach in this book has been to not only describe recent popular aspects of ED, such as basic mechanism updates, etiologic factors and pharmacotherapy, but also disease-associated ED and some future perspectives in this field.
In recent years, an increasing number of manuscripts have been published addressing the deleterious role of arginase in endothelial dysfunction. ROS have been shown to play a crucial role in arginase activation, which in turn leads to eNOS dysfunction.
Using four notorious moments in the life of Duke Vincenzo Gonzaga of Mantua, Valeria Finucci explores changing early modern concepts of sexuality, reproduction, beauty, and aging. She deftly marries salacious tales with historical analysis to tell a broader story of Italian Renaissance cultural adjustments and obsessions.
Diabetes mellitus is a metabolic disease characterized by chronic high blood glucose levels. Of the various types of diabetes, type 2 diabetes is increasing in prevalence due to obesity, aging, sedentarism, and other factors. This book presents a novel approach to preventing and treating type 2 diabetes. Chapters cover such topics as diagnosis, pathogenesis, management, lifestyle and nutritional intervention, and systems to support early diagnosis and prevention of prediabetes.
Concerns about the recent explosions of diseases like HIV, the West Nile Virus, and other avian and swine flus that originate in animals have encouraged new efforts on a global scale to bridge the gap between animal and human medicine for the benefit of both. Zoobiquity is the first book to explore many of the human and animal health issues that overlap and provides new insight into the treatment of many diseases including diabetes, cancer, heart disease and mental illness. But Zoobiquity is even bigger than health and academic medicine, and encompasses much more than our diseases and how to cure them. It sheds light on the evolution of hierarchies and similarities between a tribe of apes and a Fortune 500 company. It suggests that the ways we run our political and justice systems may overlap with how animals protect and defend their territories - and that examining this possibility in a scientifically credible way could help strengthen our institutions. It dangles the possibility that human parenting could be informed by a greater knowledge and respect for how our animal cousins solve issues of childcare, sibling rivalry and infertility.
A thrilling tale of encounters with nature’s masters of biochemistry From the coasts of Indonesia to the rainforests of Peru, venomous animals are everywhere—and often lurking out of sight. Humans have feared them for centuries, long considering them the assassins and pariahs of the natural world. Now, in Venomous, the biologist Christie Wilcox investigates and illuminates the animals of our nightmares, arguing that they hold the keys to a deeper understanding of evolution, adaptation, and immunity. She reveals just how venoms function and what they do to the human body. With Wilcox as our guide, we encounter a jellyfish with tentacles covered in stinging cells that can kill humans in mi...
An informative compendium of surprising ways you might die a horrible death at any moment from humor writers Henry Beard and Christopher Cerf.
O livro A criança intersexo: entre silenciamentos e a normalização compulsiva de corpos lança um olhar multidisciplinar sobre as violações à autonomia da criança intersexo em um cenário no qual, a partir de um "design" heteronormativo, "fabricam-se" ou "recriam-se" corpos com o auxílio da tecnologia. A obra dedica-se ao estudo de pessoas que nascem com a condição intersexo e que, por não possuírem uma anato¬mia idealizada a partir de parâmetros culturais binários, causam estranheza, levan¬do-as à estigmatização e à marginalização. À luz das perspectivas teóricas de Michel Foucault, a autora apresenta críticas ferrenhas ao saber médico que descreve a criança inter...
Toen Barbara Natterson-Horowitz naar de dierentuin van Los Angeles werd geroepen bij een aap met een hartkwaal, kwam ze tot een baanbrekend inzicht. Het zou haar werk als cardioloog en psychiater ingrijpend veranderen. Ze ontdekte dat er fascinerend veel overeenkomsten zijn tussen mensen en dieren. Dieren kunnen dezelfde ziektes krijgen als mensen. Als we weten hoe deze ziektes bij dieren kunnen worden bestreden, ligt genezing bij mensen binnen handbereik.