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This book provides an account of the recent advances in our understanding of the role of proteases under physiological and pathological conditions. It reviews the contributions that have been made in the fields of biochemistry, molecular biology, medicine, agriculture and ecology. In addition there is an account of the growing number of practical applications in biotechnology, reflecting the fact that peptidases are major targets for medical and agricultural purposes. The book shows how the numerous protease structures are essential for drug design. The contributions place special emphasis on cysteine, aspartic and metalloproteases and their role in physiological and certain pathological states. Another focus is the classification and nomenclature of peptidases and a review of those proteases currently under the most intensive investigation. The book provides an informative introduction for teachers and newcomers to the field, such as graduate students, while providing a valuable source of material and ideas for the academic and industrial researcher in areas including biochemistry, medicine, agriculture and biotechnology.
This fully updated and expanded edition covers over 10,200 programs, making it the most comprehensive documentation of television programs ever published. In addition to covering the standard network and cable entertainment genres, the book also covers programs generally not covered elsewhere in print (or even online), including Internet series, aired and unaired pilot films, erotic series, gay and lesbian series, risque cartoons and experimental programs from 1925 through 1945.
Through their application in energy-efficient and environmentally friendly devices, zinc oxide (ZnO) and related classes of wide gap semiconductors, including GaN and SiC, are revolutionizing numerous areas, from lighting, energy conversion, photovoltaics, and communications to biotechnology, imaging, and medicine. With an emphasis on engineering a
The four volume set LNAI 3681, LNAI 3682, LNAI 3683, and LNAI 3684 constitute the refereed proceedings of the 9th International Conference on Knowledge-Based Intelligent Information and Engineering Systems, KES 2005, held in Melbourne, Australia in September 2005. The 716 revised papers presented were carefully reviewed and selected from nearly 1400 submissions. The papers present a wealth of original research results from the field of intelligent information processing in the broadest sense; topics covered in the fourth volume are innovations in intelligent systems and their applications, data mining and soft computing applications, skill acquisition and ubiquitous human computer interactio...
The untold story of ferocious air and naval combat during the WWII Battle of Okinawa—drawn from primary sources and survivor interviews. This is the story of an overlooked yet significant aerial and naval battle during the American assault on Okinawa in the spring of 1945. While losses to America’s main fleet are well recorded, less well known is the terrific battle waged on the radar picket line, the fleet’s outer defense against Japanese marauders. Weaving together the experiences of the ships and their crews—drawn from ship and aircraft action reports, ship logs, and personal interviews—historian Robin L. Reilly recounts one of the most ferocious air and naval battles in history...