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Drug Discovery Toxicology
As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and application of tools and methods at each step of the drug discovery process. • Guides researchers as to what drug safety experiments are both practical and useful • Covers a variety of key topics – safety lead optimization, in vitro-in vivo translation, organ toxicology, ADME, animal models, biomarkers, and –omics tools • Describes what experiments are possible and useful and offers a view into the future, indicating key areas to watch for new predictive methods • Features contributions from firsthand industry experience, giving readers insight into the strategy and execution of predictive toxicology practices
Suicide: Phenomenology and Neurobiology
This book addresses the phenomenology, demographics, and neurobehavioral aspects of suicidal behavior and its risk factors, underscoring common neurobehavioral threads among different approaches which may underlie such extreme behavior. It additionally provides an overview of new approaches, such as imaging techniques to identify at-risk individuals or in response to drug treatment associated with suicidal behavior, neurodevelopmental approaches, genetic and epigenetic linkages to suicidal behavior, animal models of specific risk factors, as well as potential biomarkers being employed to help assess risk.
Basic Marketing
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Sharing the Earth, Dividing the Land
This collection of papers is the fifth in a series of volumes on the work of the Comparative Austronesian Project. Reflecting the unique experience of fourteen ethnographers in as many different societies, the papers in this volume explore how people in the Austronesian-speaking societies of the Asia-Pacific have traditionally constructed their relationship to land and specific territories. Focused on the nexus of local and global processes, the volume offers fresh perspectives to current debate in social theory on the conflicting human tendencies of mobility and emplacement.
Handbook of Research on Identity Theory in Marketing
The Handbook of Research on Identity Theory in Marketing features cutting-edge research that delves into the origins and consequences of identity loyalty and organizes these insights around five basic identity principles that span nearly every consumer marketing subdomain. This Handbook is a comprehensive and state of the art treatment of identity and marketing: An authoritative and practical guide for academics, brand managers, marketers, public policy advocates and even intellectually curious consumers.
Soul Resurrected (Sons of Wrath, #2)
As Wrath's fiercest son, Logan carries the scars of fifty years spent in the most dreaded prison of the underworld, for a sin he'd kill to keep secret. Enduring decades of gruesome torture has left Logan feared by and detached from others, until a female Alexi's blood resurrects his soul from death and, with it, the pleasures he's been denied for so long. Plagued by shame of her own, Calla is drawn to the ruthless demon, Logan, whose insatiable craving for her touch rouses buried passions and, for once, leaves her feeling desired. A dark and dangerous evil has been reawakened, however, and when Calla is drawn too close to its breeding grounds, Logan vows to summon the violence of Wrath in order to keep her safe. First, though, Calla must save him from a past riddled with deceit and corruption ... but only if she can accept the chilling consequences of unearthing his vilest skeleton.
Hybridity
Over the last two decades, the unstable notion of hybridity has been the focus of a number of debates in cultural and literary studies, and has been discussed in connection with such notions as métissage, creolization, syncretism, diaspora, transculturation and in-betweeness. The aim of this volume is to form a critical assessment of the scope, significance and role of the notion in literature and the visual arts from the eighteenth century to the present day. The contributors propose to examine the development and various manifestations of the concept as a principle held in contempt by the partisans of racial purity, a process enthusiastically promoted by adepts of mixing and syncretism, b...
