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The Mechanisms of DNA Replication
DNA replication is a fundamental part of the life cycle of all organisms. Not surprisingly many aspects of this process display profound conservation across organisms in all domains of life. The chapters in this volume outline and review the current state of knowledge on several key aspects of the DNA replication process. This is a critical process in both normal growth and development and in relation to a broad variety of pathological conditions including cancer. The reader will be provided with new insights into the initiation, regulation, and progression of DNA replication as well as a collection of thought provoking questions and summaries to direct future investigations.
The Neuroimmunological Basis of Behavior and Mental Disorders
For many years, the immune and central nervous systems were thought to function independently with little or no interaction between the two. This view has und- gone dramatic changes over the past three decades. Indeed, we now know that there exists various feedback loops between the brain and immune systems that impact signi cantly upon different behavioral processes, including normal behavior and mental disorders. Pioneering efforts in generating this change were initiated by a number of early investigators. Included were those whose efforts were directed at establishing neuroimmune connections as well as others whose research focused upon the relationship between immunity, cytokines, and b...
Multi-Agent-Based Production Planning and Control
At the crossroads of artificial intelligence, manufacturing engineering, operational research and industrial engineering and management, multi-agent based production planning and control is an intelligent and industrially crucial technology with increasing importance. This book provides a complete overview of multi-agent based methods for today’s competitive manufacturing environment, including the Job Shop Manufacturing and Re-entrant Manufacturing processes. In addition to the basic control and scheduling systems, the author also highlights advance research in numerical optimization methods and wireless sensor networks and their impact on intelligent production planning and control syste...
Dynamics in Logistics
The volume comprises the proceedings of the third International Conference on Dynamics in Logistics LDIC 2012. The scope of the conference targeted the identification, analysis, and description of the dynamics of logistic processes and networks. The spectrum ranged from the modeling and planning of processes and innovative methods like autonomous control and knowledge management to the new technologies provided by radio frequency identification, mobile communication, and networking. The growing dynamics in the area of logistics poses completely new challenges: Logistic processes and networks must rapidly and flexibly adapt to continuously changing conditions. LDIC 2012 provided a venue for r...
Gamma-Ray Bursts
As the most powerful explosion that occurs in the universe, gamma-ray bursts (GRBs) are one of the most exciting topics being studied in astrophysics. Creating more energy than the Sun does in its entire lifetime, GRBs create a blaze of light that will outshine every other object visible in the sky, enabling us to measure galaxies that are several million years old.GRBs cover various areas of astronomy and interest in them reaches a wide range of fields. Andrew Levan explores the fascinating history of these astronomical occurrences and details our current understanding of GRBs. The science behind them is rapidly moving and this book examines the knowledge that we now have as well as the questions that are continually being raised. Predominantly aimed at PhD students and researchers in the area, Gamma-Ray Bursts addresses this captivating topic and outlines the principles and initial applications of a fascinating astronomical phenomena.
Mechatronics in Action
Mechatronics in Action’s case-study approach provides the most effective means of illustrating how mechatronics can make products and systems more flexible, more responsive and possess higher levels of functionality than would otherwise be possible. The series of case studies serves to illustrate how a mechatronic approach has been used to achieve enhanced performance through the transfer of functionality from the mechanical domain to electronics and software. Mechatronics in Action not only provides readers with access to a range of case studies, and the experts’ view of these, but also offers case studies in course design and development to support tutors in making the best and most effective use of the technical coverage provided. It provides, in an easily accessible form, a means of increasing the understanding of the mechatronic concept, while giving both students and tutors substantial technical insight into how this concept has been developed and used.
The Microbiome in Respiratory Disease
This book comprehensively covers the microbiome in respiratory disease, from the initial research study to the disease-specific implications and related applications. Research on the respiratory microbiome is increasing in volume and scope. This reflects rapidly growing interest in the study of respiratory disease to understand how microbiota shape mechanisms of disease pathogenesis. The respiratory tract spans the nasal passages, sinus cavities, oropharynx, and the tracheobronchial tree of the lungs. In these compartments of the upper and lower respiratory tract, the microbiota have now been studied in the context of several chronic respiratory conditions. These include chronic sinusitis, a...
