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Thirty years ago, the group of Baulieu and colleagues discovered that certain steroid hormones were present in higher amounts in the brain than in the plasma, and also found that suppression of circulating steroids by adrenalectomy and castration did not affect the concentration of pregnenolone, dehydroepiandrosterone and their sulfate esters in the rat brain. These seminal observations led to the concept that the brain, in very much the same way as the adrenal cortex, testis, ovary and placenta, was capable of synthesizing steroids. These brain born steroids, called neurosteroids, have been found to exert a vast array of biological activities. A number of steroidogenic enzymes have now been identified in the central nervous system by immunohistochemistry and in situ hybridization, and the neuronal and hormonal mechanisms regulating the biosynthesis of neurosteroids have been partially elucidated. The aim of this Research Topic is to celebrate three decades of research on neurosteroids by gathering a bouquet of review papers and original articles from leading scientists in the flourishing field of neurosteroids.
Essentials of Cognitive Neuroscience guides undergraduate and early-stage graduate students with no previous neuroscientific background through the fundamental principles and themes in a concise, organized, and engaging manner. Provides students with the foundation to understand primary literature, recognize current controversies in the field, and engage in discussions on cognitive neuroscience and its future Introduces important experimental methods and techniques integrated throughout the text Assists student comprehension through four-color images and thorough pedagogical resources throughout the text Accompanied by a robust website with multiple choice questions, experiment vidoes, fMRI data, web links and video narratives from a global group of leading scientists for students. For Instructors there are sample syllabi and exam questions
An amazing journey into the hidden realm of nature’s sounds The natural world teems with remarkable conversations, many beyond human hearing range. Scientists are using groundbreaking digital technologies to uncover these astonishing sounds, revealing vibrant communication among our fellow creatures across the Tree of Life. At once meditative and scientific, The Sounds of Life shares fascinating and surprising stories of nonhuman sound, interweaving insights from technological innovation and traditional knowledge. We meet scientists using sound to protect and regenerate endangered species from the Great Barrier Reef to the Arctic and the Amazon. We discover the shocking impacts of noise po...
Encyclopedia of Reproduction, Second Edition, Six Volume Set comprehensively reviews biology and abnormalities, also covering the most common diseases in humans, such as prostate and breast cancer, as well as normal developmental biology, including embryogenesis, gestation, birth and puberty. Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers, from advanced undergraduate students, to research professionals. Chapters also explore the latest advances in cloning, stem cells, endocrinology, clinical reproductive medicine and genomics. As reproductive health is a fundamental component of an individual’s overall health status and a central ...
This book concerns how estrogens are synthesized in the brain and their two modes of action on behavior: a slow process involving gene transcription and a faster action at the cell membrane. The significance of the regulation and distribution of the estrogen synthesizing enzyme aromatase in the brain is also highlighted.
Il mondo naturale è ricco di conversazioni, molte delle quali fuori dell’intervallo di udibilità dell’orecchio umano. Oggi però gli scienziati utilizzano strumenti digitali all’avanguardia per scoprire questi suoni incredibili, che rivelano l’esistenza di fitte comunicazioni fra creature della stessa specie e di specie diverse – animali, piante, microrganismi, persino sistemi geologici. La tecnologia spesso ci distrae dalla natura, ma se invece potesse essere la chiave per riconnetterci a essa? Come in un romanzo, Karen Bakker ci conduce in un susseguirsi di storie affascinanti e sorprendenti sui suoni prodotti dalle specie viventi non umane e su come vengono percepiti; linguagg...
〈타임스〉 최고의 책 선정! 〈월스트리트저널〉 필독서 10선 선정! “테스토스테론을 성, 스포츠, 정치와 관련해 논하려면 이 남성호르몬이 우리 사회에 미치는 영향을 과학적으로 제대로 설명해야 한다. 우리는 바로 그 탁월한 책을 만났다.” _스티븐 핑커(하버드 대학교 심리학과 교수. 《우리 본성의 선한 천사》, 《마음은 어떻게 작동하는가》, 《지금 다시 계몽》의 저자) 하버드 대학교 인간 진화 생물학자 캐롤 후븐이 밝혀낸 남성호르몬 테스토스테론의 진실과 거짓! 테스토스테론은 우리 사회를 어떻게 지배해왔을까? ...