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Radiation-induced effects and the immune system
Numerous developments in molecular biology have led to an explosive growth in the knowledge underlying mechanisms of carcinogenesis, cell signalling, tumor progression and development of metastasis. However, cure of cancer is still hampered by the inherited capacity of tumors to become resistant to standard therapies, to metastasize from their initial location and to proliferate in other tissue compartments. Radiotherapy is one of the main treatment modalities to achieve locoregional tumor control. However, the treatment of distant metastases further remains to be a challenge. In this special topic we are interested to elucidate immunological aspects which are initiated and affected by radio...
Critical Issues in Head and Neck Oncology
This is an open access book. With a wealth of exciting data emerging in this rapidly evolving field this book will review the state-of-the-art knowledge with emphasis on multidisciplinary decision and management of head and neck cancer. The book provides significant detail on a wide range of topics including: the role of new targets for treatment, immunotherapy, resistance mechanisms, standardizing molecular profiling programs, and new methods to guide therapeutic approaches. In addition different disease situations are addressed including different treatment approaches in primary disease and in recurrent and/or metastatic disease as well as new developments in pathology, surgery and reconstruction techniques, new systemic therapies in salivary gland cancer, and supportive care and follow-up. All disciplines involved in the treatment of head & neck cancer are covered with a focus on translation into daily practice. The 8th-THNO is designed for medical oncologists, head and neck surgeons, radiation oncologists, otolaryngologists, and other medical professionals involved in the treatment of patients with head and neck cancer.
Tax Administration
This is a print on demand edition of a hard to find publication. Congress enacted the First-Time Homebuyer Credit (FTHBC) to assist the struggling real estate market and encourage taxpayers to purchase their first homes. Congress enacted different versions of the FTHBC -- as part of the Housing and Econ. Recovery Act of 2008; the Amer. Recovery and Reinvest. Act of 2009; and the Worker, Homeownership, and Bus. Assistance Act of 2009. The three FTHBC provisions combined may result in total revenue losses to the fed. gov¿t. of about $22 billion through 2019. This report identifies: (1) the number of FTHBC claims and dollar amounts claimed for each credit version by state; and (2) state rankings, using selected statistics, such as the total dollar amount of FTHBC claimed in each state. Charts and tables.
Aviation and the Environment
The FAA estimates that the number of flights in the U.S. will increase 20% by 2024. It also has identified numerous airports that will need to expand to handle more flights. However, increasing airport capacity and operations poses potentially significant impacts on the environment and quality of life for surrounding communities. This report addresses: (1) airports' actions to reduce their environmental impacts; (2) the extent airports believe environmental issues delay development or operational changes; and (3) the strategies airports can adopt to address environmental issues. The report surveyed the 150 busiest airports as measured by the number of operations. Illus. This is a print on demand edition of a hard to find report.
Macrophages in inflammation and its resolution
Macrophages were initially identified as a key element in the innate host response to infection and injury due to their phagocytic clearance and elimination of pathogenic and non-pathogenic entities. However, as macrophage research advanced it became clear that not only are these cells amenable to the acquisition of multiple plastic phenotypes during inflammatory responses to different pathogens, they also play a paramount role in the termination of inflammation and acquired immune responses. In addition, macrophages profoundly affect host physiology when they migrate to distant sites and differentiate to specialized cells, like foam cells, osteoclasts, adipose tissue- and tumor -associated ...
The Military as a Separate Society
The exercise of public power by the military in civilian Western democracies such as Australia and the United States demonstrates a tendency toward diminished responsibility for moral behavior. Pauline Collins argues that a different system of military criminal investigation and discipline outside the civilian justice system enables the military to operate like a coterie and can lead to a failure in the requisite moral standard of behavior required of military personnel and maintaining civilian institutional control. Collins argues that the justifications for separate treatment weakens both the military reputation and the practice of civilian control of the military as well as leading to an overall decline in morality and values in a democratic society.
Computer Vision
Computer vision has made enormous progress in recent years, and its applications are multifaceted and growing quickly, while many challenges still remain. This book brings together a range of leading researchers to examine a wide variety of research directions, challenges, and prospects for computer vision and its applications. This book highlights various core challenges as well as solutions by leading researchers in the field. It covers such important topics as data-driven AI, biometrics, digital forensics, healthcare, robotics, entertainment and XR, autonomous driving, sports analytics, and neuromorphic computing, covering both academic and industry R&D perspectives. Providing a mix of breadth and depth, this book will have an impact across the fields of computer vision, imaging, and AI. Computer Vision: Challenges, Trends, and Opportunities covers timely and important aspects of computer vision and its applications, highlighting the challenges ahead and providing a range of perspectives from top researchers around the world. A substantial compilation of ideas and state-of-the-art solutions, it will be of great benefit to students, researchers, and industry practitioners.
