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Gilles de la Tourette Syndrome (TS) is a common, albeit severely under-diagnosed, neuropsychiatric disorder that is caused by a complex genetic basis, interacting with environmental factors. High comorbidity rates with other neurodevelopmental disorders such as attention deficit/hyperactivity disorder and obsessive compulsive disorder raise the intriguing hypothesis of a shared etiological background. Abnormalities of corticostriatal-thalamic-cortical circuits (CSTC) and dysfunction of both dopamine and serotonin neurotransmitter systems are assumed to be associated with TS. Recently, multiple lines of evidence also point towards an important role of additional neurotransmitters such as hist...
Gilles de la Tourette Syndrome (TS) is a common, albeit severely under-diagnosed, neuropsychiatric disorder that is caused by a complex genetic basis, interacting with environmental factors. High comorbidity rates with other neurodevelopmental disorders such as attention deficit/hyperactivity disorder and obsessive compulsive disorder raise the intriguing hypothesis of a shared etiological background. Abnormalities of corticostriatal-thalamic-cortical circuits (CSTC) and dysfunction of both dopamine and serotonin neurotransmitter systems are assumed to be associated with TS. Recently, multiple lines of evidence also point towards an important role of additional neurotransmitters such as hist...
Tourette Syndrome offers a unique, comprehensive, and up-to-date overview of all of the main aspects related to TS, analyzing the complexity of its clinical presentation, novel viewpoints of causes and mechanisms, the best way to assess TS patients, the multifaceted and multidisciplinary treatment options. Contributed by the world leaders on TS this volume is a useful source of information for a wide audience of professionals - from clinicians and teachers to scientists in genetics, environmental risk factors and neurobiology, clinical care, and public health. Families directly affected by this disorder may also find this volume of value as they deal with the day to day realities associated with TS and related conditions.
This book offers a philosophical perspective on contemporary Tourette Syndrome scholarship, a field which has exploded over the last thirty years. Despite intense research efforts on this common neurodevelopmental condition in the age of the brain sciences, the syndrome’s causes and potential cures remain intriguingly elusive. How does this lack of progress relate to the tacitly operating philosophical concepts that shape our current thinking about Tourette Syndrome? This book foregrounds these tacit concepts and shows how they relate to “big topics” in philosophy such as time, volition, and the self. By tracing how these topics relate to current research on Tourette’s, it invites us...
Study the latest research findings by international experts! This comprehensive volume presents state-of-the-art scientific research on the therapeutic uses of cannabis and its derivatives. All too often, discussions of the potential medical uses of this substance are distorted by political considerations that have no place in a medical debate. Cannabis and Cannabinoids: Pharmacology, Toxicology, and Therapeutic Potential features fair, equitable discussion of this emerging and controversial medical topic by the world’s foremost researchers. Cannabis and Cannabinoids examines the benefits, drawbacks, and side effects of medical marijuana as a treatment for various conditions and diseases. ...
The endocannabinoid signaling system is a key modulator of central nervous function. This volume, essential reading for interested neuroscientists, provides in-depth coverage of the roles of the endocannabinoid signaling system in the neurobiology of behavior.
Digital Media as Ambient Therapy explores the ways “mental illness” can emerge from our relationships (with ourselves, others, and the world), to address the concern around what kind of relationality is conducive for “mental health” and what role digital technologies can play in fostering such relationality. Exploring the rise of ambient—that is to say, ubiquitous, surrounding, and environmental—technologies and their impact on our understanding of “mental health,” sanity, and therapy, this book critically examines the work of influential contemporary social theorists such as Hartmut Rosa and investigates case studies that reveal new modes of digitally mediated intimacy and attention, such as ASMR and QAnon. It also poses the question of what “mental health” and “mental illness” mean for subjects increasingly faced with a maddening sense of interconnectedness. This book offers new perspectives for academics and postgraduates interested in critical discussions of alienation, digital technology, and contemporary social theory.
A collection of essays, fictions, and interviews exploring the weird temporalities of finance and catastrophe. Once, financial practitioners plied a hybrid trade as hydrologists, star-gazers, and weather-watchers who sought to discover the natural laws of value and exchange as they did the divine order of an unchanging nature. Today, corporate firms hire trend forecasters and scenario planners to play out strategic fictions in virtual worlds. Hurricane insurance markets simulate a turbulent climate to offer investment instruments to hedge against the risks of the stock market. And for financial astrologers operating in the city of London, celestial motions provide a cosmic map that orients t...
Psychische Erkrankungen gehoren epidemiologisch weltweit zu den verbreitetsten Krankheitsrisiken. Psychopharmaka pragen unsere Gesellschaft starker, als uns dies bewusst ist. Gleichwohl ist der rechtliche Rahmen der psychopharmakologischen Forschung und Therapie fragmentiert sowie teils von vorrationalen Pfadabhangigkeiten gepragt. Die vorliegende Untersuchung geht von der Geschichte der wissenschaftlichen Psychopharmakologie sowie den neurochemischen Wirkungsmechanismen typischer Psychopharmaka aus. Klaus Ferdinand Garditz analysiert die wildwuchsigen Regelungsstrukturen und die damit verbundenen Wechselwirkungen zwischen Pharmakologie, Gesellschaft und Recht als institutionelle Herrschafts...