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Pharmacology of Mitochondria
This special book is conceived to highlight mitochondrial structural and functional integrity and how they are associated with several human diseases such as cardiovascular, cancer, renal, neurological disorder, and genetic disorders. The chapters contributed by leading mitochondrial researchers in the handbook will take us through the novel pharmacological strategies via mitochondria to understand their physiological and pathological role as well as present them as therapeutic targets.
Target Assays for Modern Herbicides and Related Phytotoxic Compounds
Target Assays for Modern Herbicides and Related Phytotoxic Compounds is a laboratory guide that features 38 comprehensive contributions to determine and quantitate the inhibition activity of modern herbicides and related phytotoxic compounds at their targets. Using algal or higher-plant model species as well as cell-free enzymatic systems, assays are described for use with modern equipment typically found in a biochemical laboratory. Many details of the tests described in this volume are being published for the first time. Assays discussed include carotenoid and chlorophyll biosynthesis and degradation, photosynthetic electron transport, amino acid biosynthesis, fatty acid formation, and cel...
QSAR and Drug Design: New Developments and Applications
Based on topics presented at the Annual Japanese (Quantitative) Structure-Activity Relationship Symposium and the Biennial China-Japan Drug Design and Development conference, the topics in this volume cover almost every procedure and subdiscipline in the SAR discipline.They are categorized in three sections. Section one includes topics illustrating newer methodologies relating to ligand-receptor, molecular graphics and receptor modelling as well as the three-dimensional (Q)SAR examples with the active analogue approach and the comparative molecular field analysis. In section 2 the hydrophobicity parameters, log P (1-octanol/water) for compound series of medicinal-chemical interest are analysed physico-organic chemically. Section 3 contains the examples based on the traditional Hansch QSAR approach.A variety of methodologies and procedures are presented in this single volume, along with their methodological philosophies.
Advances in Heterocyclic Chemistry
Advances in Heterocyclic Chemistry
EFL Learners' Acquisition of the English Article System
This book addresses several issues that have been controversial in the literature surrounding second language (L2) acquisition, including the role that the first language (L1) plays in development, the ability of L2 learners to acquire properties of functional categories not realised in their L1, the nature of L2 development itself, and the extent to which such development is constrained by innate linguistic capacities (universal grammar). These issues are considered by investigating the acquisition of the English articles by speakers of an L1 that has an article system encoding definiteness (Arabic), and an L1 that lacks articles (Japanese), at different proficiency levels in English. Those who will find this book useful include policy makers in language education as well as students and their teachers. Researchers in the field of second language acquisition can benefit from reading this book to keep abreast of the latest developments in this area in the hope of stimulating further research.
Crop Safeners for Herbicides
Crop Safeners for Herbicides aims to discuss the issue of chemical manipulation of crop tolerance to herbicides. This book resulted from a symposium titled ""Chemical Manipulation of Crop Tolerance to Herbicides"". Several chapters included herein are added contributions from experts outside of the symposium. The book not only serves as reference for the knowledge of the agronomic uses, development, chemistry, and mechanisms of action herbicide safeners, but it also assesses the impact of safeners all around the world. It also presents a discussion on alternative approaches that increases herbicide selectivity and explores future trends. Comprised of 16 chapters and divided into four parts, ...
Lake Biwa: Interactions between Nature and People
Although, the first edition had a similar focus, more than five years have passed since its publication and the biological and social circumstances of the lake have drastically changed due to, for example, the further expansion of alien species, the decrease of indigenous species, the progress of integrated watershed management by the Union of the Kansai Government which was established in 2010, the legislation of the Conservation and Restoration Act of Lake Biwa in 2015 and more. The new edition will therefore feature updated and new information on the above and more topics as well as updated and revised data based on the latest research. Inventories of respective taxa, especially those of ...
