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This book offers a comprehensive overview of the most important neurochemicals and approaches everything from the neurochemical’s perspective. It attempts to integrate the biochemical pathways of synthesis and metabolism of these neurochemicals with the disease states and point out the avenues of diagnostic testing and therapeutic intervention. Each chapter focuses on a specific neurochemical and provides a brief history, the biochemical profile, metabolism, physiological functions, and the clinical aspects. The clinical part of each chapter includes a discussion on disease states with either increased or reduced activity of the neurochemical and either activation or inhibition of the relevant receptors. This book is targeted toward practitioners and students of neuroscience and is written to emphasize the importance of these neurochemicals in the brain. With this emphasis on background neurochemical processes, the readers will be pointed towards logical diagnostic studies, laboratory investigations, and therapies based on the neurochemical dysfunction that underlies various disease states.
A comprehensive review of the recent developments in microbial bioprotectants Covers key classifications of bioprotectants: bacterial (e.g. Bacillus spp.), fungal (e.g. Trichoderma spp.), and viral (e.g. bacteriophages) Discusses the general issues that arise with the use of key bioprotectants throughout agriculture (e.g. risk of development of resistance against bioprotectants)
Psychopharmacology, Volume 2: Preclinical Psychopharmacology presents the mechanism of action of antidepressant drugs and neuroleptics. This book discusses the significance of the interaction between various neurotransmitter system in both biochemical and functional consequences of repeated drug administration. Organized into 12 chapters, this volume begins with an overview of the effects of antidepressant drugs on norepinephrine metabolism. This text then discusses the different aspects of monoamine oxidase and its inhibitors. Other chapters consider the mechanism of action of lithium, which requires consideration of some of the general characteristics of periodic behavior. This book discusses as well the preclinical aspects of tranquilizers, particularly those dealing with benzodiazepines and non-benzodiazepines acting through the benzodiazepine receptor. The final chapter deals with the various behavioral and electrophysiological effects of cocaine in animals, which presumably reflect both local anesthetic properties and action on monoamine mechanisms. This book is a valuable resource for neuropharmacologists and practicing psychiatrists.
International Review of Neurobiology
One of the principal characteristics of the European Neolithic is the development of monumentality in association with innovations in material culture and changes in subsistence from hunting and gathering to farming and pastoralism. The papers in this volume discuss the latest insights into why monumental architecture became an integral part of early farming societies in Europe and beyond. One of the topics is how we define monuments and how our arguments and recent research on temporality impacts on our interpretation of the Neolithic period. Different interpretations of Göbekli Tepe are examples of this discussion as well as our understanding of special landmarks such as flint mines. The ...
Reveals an Emerging Avenue of Potential Treatments for a Host of Challenging Diseases and Disorders The H3 receptor is known to play a major role in a range of CNS disorders, including those affecting cognitive functions such as ADHD and Alzheimer’s disease, as well as sleep disorders, obesity, epilepsy, schizophrenia, depression, and neurodegeneration. In light of dramatic advances in research at the molecular level, supported by impressive clinical studies, optimism remains high that an H3 receptor-related drug could hit the market soon. The Third Histamine Receptor: Selective Ligands as Potential Therapeutic Agents in CNS Disorders provides a thorough grounding in advances made over the...
Monthly, with annual cumulation. Recurring bibliography from MEDLARS data base. Index medicus format. Entries arranged under subject, review, and author sections. Subject, author indexes.