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Lectures on Differential and Integral Equations
Lucid, self-contained exposition of theory of ordinary differential equations and integral equations. Boundary value problem of second order linear ordinary differential equations, Fredholm integral equations, many other topics. Bibliography. 1960 edition.
Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Rethinking Identity in Modern Japan
Examining the creative and academic works of a number of influential Japanese thinkers, this volume is a major reconsideration of Japanese late modernity and national hegemony.
Gastric Cancer
Gastric cancer is still the most common cause of cancer death in the world, although in most countries, with the notable exception of the United States, its incidence is slowly declining. In statistical terms, gastric cancer is therefore the most formidable of cancer types, and its control is a pressing issue. Recent evidence indicates that the conversion of normal cells to so-called "clinical cancer" is the prerequisite for a multistage process which is intimately associated with an accumulation of multiple gene alterations including both oncogenes and tumor-suppressor genes. Gastric cancer is no exception, in that it reveals multiple gene changes whose scenario differs, depending on their ...
Lipases and Phospholipases in Drug Development
Lipases and Phospholipases are key control elements in mammalian metabolism. They share many common features that set them apart from other metabolic enzyme classes, most importantly their association with biological membranes. Their potential as drug targets for the treatment of metabolic diseases is widely recognized, and the first lipase inhibitor drugs have been successfully introduced. Providing drug developers with a firm foundation for lipase-centered drug design, the editors of this volume have assembled experts from different scientific disciplines to create a comprehensive handbook for all pharmaceutical chemists, biochemists and physiologists working with lipases. The authors examine fundamental aspects of lipase function in vitro and in vivo, explaining how this knowledge may be used to develop lipase assays. They also treat the physiological roles of lipases in normal and disordered metabolism, as well as strategies to target lipases for the treatment of diabetes, obesity and related disorders. Additional topics include the application of phospholipases for liposome-based drug delivery and their use as diagnostic tools.
