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This is the first full-length, systematic study in English of Isaac Breuer, a founder of Agudat Israel, whose intellectual achievements reflected the world of Franz Rosenzweig and Martin Buber in an Orthodox mirror. It sheds light on an often neglected aspect of German Jewry's last phase and reclaims Breuer as a paradigmatic figure in the Jewish encounter with modernity.
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Vitamins and Hormones
'Cannabinoids' is a broad term covering a group of natural products from Cannabis sativa, one of which locks on to specific receptors – protein molecules on the surface of cells – known as cannabinoid receptors. Over the past decades scientists have found that cannabinoid receptors and their endogenous ligands, the endocannabinoids, are involved in a vast array of physiological functions, including helping to control brain activity, energy metabolism, heart function, the immune system and even reproduction. In Cannabinoids, Vincenzo Di Marzo has assembled contributions from international experts to provide the definitive guide to what continues to be a rapidly developing research field. After an introductory historical chapter, the book continues by looking at the biochemical, genetic and molecular elements of cannabinoids, followed by chapters covering their role in health and disease. The final chapter outlines the need for a new nomenclature to reflect the complex and multi-disciplinary nature of this area.
The endocannabinoid system consists of cannabinoid receptors, their endogenous lipid ligands (endocannabinoids) and the enzymatic machinery for their synthesis and degradation. In the brain, endocannabinoids regulate ion channel activity and neurotransmitter release and thereby contribute to various aspects of brain function, including memory, reward and emotions. Their ability to modulate synaptic efficacy has a wide range of functional consequences and provides unique therapeutic possibilities. Unprecedented advances have been made in the understanding of the role of endocannabinoids in the regulation of the emotional brain over the past few years. However, a comprehensive book encompassing all these aspects is still lacking. The book will provide an overview of the role played by the endocannabinoid system in the regulation of emotional processes with particular emphasis on the modulation of memory and reward for emotionally arousing events and for the regulation of motivational aspects in cannabis use.
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
This thesis investigates passively mode-locked semiconductor lasers by numerical methods. The understanding and optimization of such devices is crucial to the advancement of technologies such as optical data communication and dual comb spectroscopy. The focus of the thesis is therefore on the development of efficient numerical models, which are able both to perform larger parameter studies and to provide quantitative predictions. Along with that, visualization and evaluation techniques for the rich spatio-temporal laser dynamics are developed; these facilitate the physical interpretation of the observed features. The investigations in this thesis revolve around two specific semiconductor dev...