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Contents: --pt. 1. U.S. Dept. of Agriculture. --pt. 2. State agricultural colleges and experiment stations.
The availability of well-defined genetic strains and the ability to create transgenic and knockout mice makes mouse models extremely valuable biomedical tools. Their suitability as an experimental system for cardiovascular research depends on the individual investigator’s ability to manipulate the mice surgically. Many mouse models require microsurgical techniques, which hitherto could not be performed without practical training. This comprehensive handbook enables scientists to develop these models in their own laboratories. A Handbook of Mouse Models of Cardiovascular Disease is the first book to address pathology in mouse models of heart disease, providing the reader with essential info...
This revised and updated new edition of a successful book is a multidisciplinary, comprehensive guide to occupational factors of malignant diseases. Building on the first edition, new research discoveries and their consequences in our understanding on carcinogenic mechanisms, diagnosis and attribution of occupational cancers are discussed. Examples of such discoveries are germline and acquired mutations of BAP1 in malignant mesothelioma, which have led to changes in diagnostic criteria, and carcinogen-specific genetic and epigenetic alterations in lung cancer. There are several new chapters, including gastrointestinal cancers, epidemiology of lung cancer, cancer of thyroid, and the role of primary health care in occupational cancer control. Occupational Cancers is aimed at experienced and trainee oncologists, pathologists, clinicians in occupational health, and pulmonologists, as well as epidemiologists, clinical researchers, lawyers and public health officials.
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