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Advanced Methods of Pharmacokinetic and Pharmocodynamic Systems Analysis Volume 3 is vital to professionals and academicians working in drug development and bioengineering. Both basic and clinical scientists will benefit from this work. This book contains chapters by leading researchers in pharmacokinetic/pharmacodynamic modeling and will be of interest to anyone involved with the application of pharmacokinetic and pharmacodynamics to drug development. The use of mathematical modeling and associated computational methods is central to the study of the absorption, distribution and elimination of therapeutic drugs (pharmacokinetics) and to understanding how drugs produce their effects (pharmac...
In The Headless Republic, Jesse Goldhammer explores how the French revolutionaries retrieved a set of ideas about founding violence from the classical Romans and early Christians and incorporated it into postrevolutionary debates that echoed into the twentieth century. By linking sacrifice as expressed in revolutionary practices to modern French theory, Goldhammer shows how ancient ideas of violent political renewal made their way into the contemporary age.Goldhammer elucidates the theoretical and practical significance of sacrificial violence during the Revolution, and then turns his attention to postrevolutionary intellectuals whose work is inspired by the founding sacrifices of the French...
The author here presents an architectural history of Paris, stretching from the 3rd century BC up until the end of the 20th century.
Differential Equations and Applications
Democracy is perhaps the defining characteristic of modern Western society, but even as late as the nineteenth century it was often viewed with suspicion by many who saw it as akin to anarchy and mob rule. It was not until the French and American revolutions of the eighteenth century that electoral democracy began to gain momentum as a serious force, which was eventually to shape political discourse on a broad, international scale. Taking as its focus the French Revolution, this book explores how the experience in France influenced the emergence of electoral democracy, arguing - contrary to recent revisionist studies - that it was indeed the progenitor of modern representative democracy. Rej...
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This handbook is volume III in a series devoted to stationary partial differential quations. Similarly as volumes I and II, it is a collection of self contained state-of-the-art surveys written by well known experts in the field. The topics covered by this handbook include singular and higher order equations, problems near critically, problems with anisotropic nonlinearities, dam problem, T-convergence and Schauder-type estimates. These surveys will be useful for both beginners and experts and speed up the progress of corresponding (rapidly developing and fascinating) areas of mathematics.Key features: - Written by well-known experts in the field- Self-contained volume in series covering one of the most rapid developing topics in mathematics- Written by well-known experts in the field- Self-contained volume in series covering one of the most rapid developing topics in mathematics
Analytical and Numerical Approaches to Asymptotic Problems in Analysis
An account of the relationship between Louis XV, the clergy of France, and the Parlement of Paris in the mid-eighteenth century.