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This volume, written by well-known experts in the field, covers all aspects of Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis (AAV). The expression refers to a group of diseases, characterized by destruction and inflammation of small vessels. The clinical signs vary and affect several organs, such as the kidney, lung, skin, nervous system and others. The opening chapters give some historical hints, explain the genetic basis of the disease and provide insights into the pathogenesis derived from recent experimental studies and guides the reader through classification and nomenclature. A large part of the book is then devoted to a detailed description of the specific related ...
A pediatric perspective Our daily food intake not only provides the calories and the macro- and micronutrients necessary for survival - nutrients also have a tremendous potential to modulate the actions of the immune system, a fact which has a significant impact on public health and clinical practice. This book presents the latest findings on how nutrient status can modulate immunity and improve health conditions in pediatric patients. Divided into three parts, it covers major aspects of the interplay between nutrients and the regulation of immunity and inflammatory processes. Part one deals with the pharmaceutical value of specific amino acids (arginine and glutamine) and hormones for addressing immune disorders and infant development. The second part revolves around gut function and immunity, and the right balance of probiotics. The final part explores the role of lipid mediators and how their types and proportions can tip the balance in favor of health and disease.
The Italian Gothic horror genre underwent many changes in the 1980s, with masters such as Mario Bava and Riccardo Freda dying or retiring and young filmmakers such as Lamberto Bava (Macabro, Demons) and Michele Soavi (The Church) surfacing. Horror films proved commercially successful in the first half of the decade thanks to Dario Argento (both as director and producer) and Lucio Fulci, but the rise of made-for-TV products has resulted in the gradual disappearance of genre products from the big screen. This book examines all the Italian Gothic films of the 1980s. It includes previously unpublished trivia and production data taken from official archive papers, original scripts and interviews with filmmakers, actors and scriptwriters. The entries include a complete cast and crew list, plot summary, production history and analysis. Two appendices list direct-to-video releases and made-for-TV films.
Presenting the New Edition of the classic reference on pediatric hematology and oncology. Comprehensively revised and updated, it continues to integrate lucid reviews of the pathophysiology of disease with detailed clinical guidance on its diagnosis and management. Drs. Nathan and Orkin - joined by two new co-editors and an outstanding team of authors - worked tirelessly to ensure that all the latest scientific advances appear in the 6th Edition.
The "Gothic" style was a key trend in Italian cinema of the 1950s and 1960s because of its peculiar, often strikingly original approach to the horror genre. These films portrayed Gothic staples in a stylish and idiosyncratic way, and took a daring approach to the supernatural and to eroticism, with the presence of menacing yet seductive female witches, vampires and ghosts. Thanks to such filmmakers as Mario Bava (Black Sunday), Riccardo Freda (The Horrible Dr. Hichcock), and Antonio Margheriti (Castle of Blood), as well the iconic presence of actress Barbara Steele, Italian Gothic horror went overseas and reached cult status. The book examines the Italian Gothic horror of the period, with an abundance of previously unpublished production information drawn from official papers and original scripts. Entries include a complete cast and crew list, home video releases, plot summary and the author's analysis. Excerpts from interviews with filmmakers, scriptwriters and actors are included. The foreword is by film director and scriptwriter Ernesto Gastaldi.
Chronic liver failure is a frequent condition in clinical practice that encompasses all manifestations of patients with end-stage liver diseases. Chronic liver failure is a multiorgan syndrome that affects the liver, kidneys, brain, heart, lungs, adrenal glands, and vascular, coagulation, and immune systems. Chronic Liver Failure: Mechanisms and Management covers for the first time all aspects of chronic liver failure in a single book, from pathogenesis to current management. Each chapter is written by a worldwide known expert in their area and all provide the latest state-of-the-art knowledge. This volume is specifically designed to provide answers to clinical questions to all doctors dealing with patients with liver diseases, not only clinical gastroenterologists and hepatologists, but also to internists, nephrologists, intensive care physicians, and transplant surgeons.
Housecraft, and Statecraft offers a unique perspective on Venice and Venetian society as the city evolved from a merchant-dominated regime in the fifteenth century into an aristocratic oligarchy in the sixteenth. It traces the growth, within the elite, of a new sense of hierarchy and honor.
Human beings cannot live without travelling. Nowadays, old, outdated ideas are waning and it is time for an intellectual journey into complexity. Life and all that stems from it is far from equilibrium, in a continuous search for the new and the improbable. This book is a smooth journey into the complexity theory addressed to managers, entrepreneurs, practitioners; especially, it is an invitation to embark on the continuous search for the creative moment, where each arrival is a new departure. Those who want to imagine their future, those who have a dream will be inspired to venture into the mysterious and charming land at the edge of chaos, being aware that their future may also depend on chance.