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Dengue and Zika: Control and Antiviral Treatment Strategies
This contributed volume contains 25 chapters from leading international scientists working on dengue and Zika viruses, who came together in Praia do Tofo in Mozambique to discuss the latest developments in the fields of epidemiology, pathogenesis, structural virology, immunology, antiviral drug discovery and development, vaccine efficacy, and mosquito control programs. The meeting venue offered an opportunity to discuss current research on these flaviviruses in an idyllic setting, and also to develop first-hand appreciation of the issues in infectious diseases facing developing countries and of the research gaps in Africa. For readers, who should include basic and clinical researchers in the field and public health professionals, the chapters are organized to provide a comprehensive overview of the various topics in current dengue and Zika virus research. A unique feature of the proceedings of this meeting is the inclusion of the discussions that took place following presentations. These have been transcribed and appended to the end of the relevant chapters, and they form the “salt in the soup” of this book.
Nutrition, Metabolism and Infection
The role of nutritional status in the risk and course of infection is actively being investigated. Being involved in the normal function and modulation of all the biological processes, including the maintenance of healthy mucosal barriers and immune responses, macro - and micro - nutrients have a pleiotropic effect on the host health. During the last decade, it has been demonstrated that nutrients, or their lack of, influence the susceptibility to infection and how the metabolic changes that occur during host-pathogen interaction impact on pathogen proliferation and pathogenicity.
Laura Laura
"[Francis] is just so good at the transcription and transformation of everyday ordinary life, all seen from sideways on, so that everything becomes so strange and so funny."–Tessa Hadley An elderly academic is accosted by a homeless woman on his way home from the cinema. She tells him her name is Laura. So begins a nightmarish journey for Gerald, who is forced to confront the mystery of his own past and to ask himself if he has lived a good life – or even a decent one. In the course of this very funny, sometimes disturbing and often moving novel, suppressed memories return to haunt him, including the question of the role he played in a family tragedy. Above all he has to assess the harm he may have done in a long-forgotten love affair. Those close to him suddenly appear unfathomable as he begins to question if he truly knows those closest to him and even himself. The problem with exploring the past, Gerald begins to see, is that there are an infinite number of ways to travel through it.
A Thousand Lies
It's often said that a picture paints a thousand words... but what if every single one is a lie? In 1987, 36-year-old Sheila Shand was given a suspended sentence for killing her father. At her trial, it emerged that she and her mother and sister had been forced to shield brutal sadist Leslie Shand while he subjected them to a reign of terror, daily beatings and sexual abuse. Years later, journalist Amy Vaughan discovers a newspaper cutting about the Shand case while clearing out her dead mother's flat. Concluding that they are related, she decides to visit Sheila's mother Iris, who is in a care home. Amy is curious about the elderly woman who pores endlessly over an album of family snaps because she has known, from an early age, that photographs tell lies. Her own mother, who suffered from Munchausen's Syndrome By Proxy, used snaps of the daughter she'd made sick to try and keep the affections of Amy's father, a charismatic but elusive conman. When she begins to investigate the Shand case, Amy realises that there is more to the murder of Leslie than the police ever unearthed, including two long-buried skeletons in woods near the family's home...
An Echo of Scandal
In the dead of night, with blood on her hands, she made her escape. Accused of murder, Alejandra flees her home, escaping to the southern edge of Spain, where she faces a life of poverty and destitution. Seduced by the power of the rich and the anonymity that waits across the water in Tangier, Ale makes a bid for a new start. But it will come at a cost: a life of deception. Because Ale's new friends want to know what she is running from, they want to know who she is and whether they can trust her. Fifty years later, a young American writer wanders the streets of Tangier, searching for inspiration. When he stumbles across a trace of Ale's life, he finds himself tangled in a story of scandal, love and danger that has not yet reached its end.
Telling Lies to Alice
Six years after the apparent suicide of her fiancé, Lenny Maxted, a member of Britain's best-loved comedy team, Alice Conway discovers how dangerous Lenny's former stage partner is when he reenters her life.
Laura
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