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Brain metastases are the most dreaded complication of systemic cancer, affecting some 170,000 people a year, a far greater incidence than primary brain tumors. This book presents current information on the presentation and management of patients with brain metastases, providing available data, giving guidelines that can be applied in day to day practice, updated information for neurosurgeons, radiation oncologists, medical oncologists, and neuron-oncologists, and as an overview for physicians in training.
There are two types of brain tumours: primary brain tumours that originate in the brain and metastatic (secondary) brain tumours that originate from cancer cells that have migrated from other parts of the body. Primary brain cancer rarely spreads beyond the central nervous system, and death results from uncontrolled tumour growth within the limited space of the skull. Metastatic brain cancer indicates advanced disease and has a poor prognosis. Primary brain tumours can be cancerous or non-cancerous. Both types take up space in the brain and may cause serious symptoms (e.g., vision or hearing loss) and complications (e.g., stroke). All cancerous brain tumours are life threatening (malignant) because they have an aggressive and invasive nature. A non-cancerous primary brain tumour is life threatening when it compromises vital structures (e.g., an artery). This book brings together the leading research in this dynamic area of research.
In Cancer Neurology in Clinical Practice, leading neuro-oncologists from around the world comprehensively review the neurologic symptoms that cancer patients experience, and show how they should be interpreted and evaluated. Organized by both symptom and organ, the book carefully describes each diagnostic neurologic entity-from symptomatology to diagnostic studies to management and prognosis-and presents each major type of cancer in terms of it neurologic problems and how they should be handled. The role of surgery, radiation, chemotherapy, and other palliative measures are considered for each type of problem. Multidisciplinary and up-to-date, Cancer Neurology in Clinical Practice explains to the busy physicians treating cancer patients the latest findings in neuro-oncology that will help them to focus their differential diagnosis, diagnostic strategy, and treatment plan for the cancer patient with neurologic symptoms and findings.
Treatment of patients with a brain tumor remains one of the most challenging and difficult areas of modern oncology. Recent advances in the molecular biology of these neoplasms have improved our understanding of the malignant phenotype and have lead to the development of novel forms of chemotherapy, including "targeted agents. The Handbook of Brain Tumor Chemotherapy reviews the state-of-the-art of chemotherapy development and clinical treatment of patients with this devastating disease. Handbook of Brain Tumor Chemotherapy offers a unique cutting-edge compendium of basic science and clinical information on the subject of brain tumor chemotherapy, reviewing what has been accomplished thus fa...
Neurological Complications of Systematic Cancer and Antineoplastic Therapy provides an in-depth review of common manifestations related to neurology that occur in patients with systemic cancer. These include brain metastases, spinal cord compression, cerebrovascular events, and leptomeningeal disease. The book also discusses less common complicatio
A review of state-of-the-art therapies currently used with leptomeningeal cancer patients, including information on symptom management, new clinical trials, epidemiology, as well as research in animal models for experimental treatments.
Cancer is a group of different diseases (more than 100) characterised by uncontrolled growth and spread of abnormal cells. Cancer can arise in many sites and behave differently depending on its organ of origin. If a cancer spreads (metastasises), the new tumour bears the same name as the original (primary) tumour. Significant progress has been made in recent years in the battle against cancer and in understanding its underlying biological mechanisms. This research progress has resulted in many experimental treatments and cures. This book presents new and important research from around the world.
"If it is true that a picture is worth a thousand words, a visual memory of a good clinical case will be retained and absorbed in a way that traditional text readings are not. Abundantly illustrated throughout, Case-Based Neurology offers an overview of a wide range of common neurological conditions. Organized by chief complaint and presented in a consistent format, each case includes history, "stop and think" questions, physical examination, laboratory testing, imaging findings, diagnosis, and discussion, including differential diagnosis and treatment. References and suggested readings follow for further study. Case-Based Neurology provides a broad selection of cases drawn from all major ar...
Despite the availability of many effective treatments, there remains a therapeutic nihilism associated with brain tumors. This highly readable second edition of 'Fast Facts: Brain Tumors' challenges this view, starting from the premise that patients with brain tumors can truly benefit from a thoughtful multidisciplinary approach. This comprehensive handbook covers all the salient features of the various brain tumors and treatment modalities in a way that will be useful to the practicing clinician. • Advances in radiology and pathology that have led to more precise and detailed diagnoses • Developments in molecular biology and imaging techniques that have improved available diagnostic mod...
An essential update of recent clinical trials in the management of neurological and neuropsychiatric disorders.