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This volume is the first comprehensive overview of Roman experimental archaeology, exploring its key themes, methodologies and applications through a diverse array of international case studies. Experiments, simulations and reconstructions are important methods for understanding the past, from uncovering how ancient objects and structures were made, used, destroyed, deposited and affected underground, to illuminating the experiences of tasting ancient foods, fighting alongside comrades or living in replicated structures. Although the incorporation of experimentation has had great success in prehistoric studies, greater reliance on the wealth of literary and material sources remaining from th...
The Story of Garum recounts the convoluted journey of that notorious Roman fish sauce, known as garum, from a smelly Greek fish paste to an expensive luxury at the heart of Roman cuisine and back to obscurity as the Roman empire declines. This book is a unique attempt to meld the very disparate disciplines of ancient history, classical literature, archaeology, zooarchaeology, experimental archaeology, ethnographic studies and modern sciences to illuminate this little understood commodity. Currently Roman fish sauce has many identities depending on which discipline engages with it, in what era and at what level. These identities are often contradictory and confused and as yet no one has attem...
Probiotic Dairy Products, 2nd Edition The updated guide to the most current research and developments in probiotic dairy products The thoroughly revised and updated second edition of Probiotic Dairy Products reviews the recent advancements in the dairy industry and includes the latest scientific developments in regard to the 'functional' aspects of dairy and fermented milk products and their ingredients. Since the publication of the first edition of this text, there have been incredible advances in the knowledge and understanding of the human microbiota, mainly due to the development and use of new molecular analysis techniques. This new edition includes information on the newest development...
Analytik von Naturstoffen, die jeder kennt: Die Autoren dieses Bandes beschränken sich nicht auf die nüchterne Abhandlung von Daten und Verfahren, sondern erzählen die wahrhaft inspirierenden Geschichten jedes ihrer Moleküle. Dabei ist der rein methodische Teil so ausführlich und exakt beschrieben, dass der Band hervorragend für Lehre und Studium geeignet ist. Übungsaufgaben mit Lösungen und das attraktive Layout machen das Buch zu einem Muss für jeden Organiker und Spektroskopiker und die, die es werden wollen.
Bronchiectasis is a hot topic in respiratory medicine, attracting an increasing amount of interest from clinicians, scientists, physiotherapists and the pharmaceutical industry. However, there is a lack of knowledge about the disease in terms of the research performed, clinical management, classification and patient treatment. The disease is also very complex because it can be caused by multiple underlying disorders, meaning its clinical presentation is highly diverse. This Monograph will tackle these issues by providing a series of chapters from recognised world experts covering: clinical management, service delivery, pathophysiology, microbiology and underlying disorders. The book also addresses the challenges faced in clinical trials and the need for drug development, and presents a number of clinical cases designed to aid learning. The Bronchiectasis Monograph substantially integrates the 2017 ERS guidelines on management of these patients. It is an essential reference for anyone caring for bronchiectasis patients or engaged in bronchiectasis research.
This book analyzes all aspects of metronomic chemotherapy, a new approach involving low-dose, long-term, and frequently administered therapy that has preclinical and clinical activity in various tumors. After an opening section on the pharmacological bases of metronomic chemotherapy, including its antiangiogenic effects and impact on immunity, preclinical studies on various classes of drug are discussed. Clinical applications of metronomic chemotherapy in a wide variety of tumors are then addressed in detail, with description of the results of all published studies. The clinical pharmacology of metronomic chemotherapy is also considered in depth, encompassing pharmacokinetics, pharmacogenetics, pharmacoeconomics, and adverse drug reactions. The book closes by describing the role of this therapy in the veterinarian clinic.
This book provides all the information required for the optimal use of nuclear medicine techniques, which are undergoing rapid development yet remain underutilized. Each chapter focuses on one particular clinical system or disease area. The first section of each chapter illustrates normal patterns observed on commonly and uncommonly performed scans as a reference and explains when and how the procedures should be performed. The following section illustrates both the imaging patterns of different diseases and the diagnostic role of individual studies. Comparisons with other modalities are provided, and the rationale for and effective utilization of each study are discussed. The volume includes near 250 case reviews. In addition, the normal patterns on relevant morphologic modalities are documented in an appendix. The book is directed at Nuclear Medicine physicians and technologists with different levels of training and expertise and also at radiologists who practice nuclear medicine and radiology residents.
Soon after the first description of monoclonal antibodies in 1976, there was enormous interest in the clinical application of antibodies, especially in the context of cancer. Antibodies appeared to offer the “magic bullet” that would allow the specific destruction of neoplastic cells. H- ever, many years’ effort resulted in very few cases of successful immu- therapy with antibodies. As a result there was a major backlash against antibody therapy, and the field lost a considerable amount of popularity. Fashion, in science as well as in other things, tends to be cyclical. Antibody-based therapy is once again attracting scientists and clinicians. There are several reasons for the renewed ...
Roman Cookery unveils one of Europe's last great culinary secrets – the food eaten by the ordinary people of ancient Rome. Based on olive oil, fish and fresh vegetables, it was the origin of of the Mediterranean diet as we know it today and, in particular, of classic Italian cooking. Mark Grant, researcher extraordinaire, has unearthed everyday recipes like Tuna Wrapped in Vine Leaves, Olive Oil Bread Flavoured with Cheese, and Honeyed Quinces. Like an archaeologist uncovering a kitchen at Pompeii, he reveals treasures such as Ham in Red Wine and Fennel Sauce, Honey and Sesame Pizza, and Walnut and Fig Cakes. The Romans were great lovers of herbs, and Roman Cookery offers a delicious array of herb sauces and purées, originally made with a pestle and mortar, but here adapted, like all these dishes, to be made with modern kitchen equipment. This revised and expanded edition includes previously unknown recipes, allowing the reader to savour more than a hundred simple but refined dishes that were first enjoyed more than two millennia ago.
The book contains chapters written by leaders in the research on the structure and function of respiratory complex I. It will provide a concise and authoritative summary of the current knowledge on complex I of respiratory chains. This enzyme is central to energy metabolism and is implicated in many human neurodegenerative diseases, as well as in aging. Until recently it was poorly understood on a structural level, and this book will provide a timely reference resource. Such a book was not published previously. The last time a minireview series on complex I were published was in 2001, and since then complex I field changed quite dramatically.