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Human pluripotent stem cells (hPSCs) are advantageous cell sources for disease remodeling and drug screening, particularly for regenerative medicine. State-of-the-art updates have highlighted the feasibility of hPSCs for the large-scale preparation of diverse kinds of stem cells and functional cells, such as mesenchymal stem/stromal cells (MSCs), hematopoietic stem cells (HSCs), neural stem cells (NSCs), natural killer (NK) cells, and chimeric antigen receptor-transduced T cells (CAR-Ts). With the aid of preclinical investigations and clinical practice, hPSCs have been recognized as promising therapeutic cell sources with excellent properties for treating a variety of refractory and recurrent diseases. This book provides a comprehensive overview of advances in pluripotent stem cells.
In this first English-language examination of the uprisings that took place in Guizhou during the 1850s and 1860s, Robert Jenks not only provides readers with a reconstruction of the complex series of events that made up the rebellion but argues convincingly against its accepted characterization as a purely ethnic conflict-a "Miao" rebellion.
Osteoarthritis is the most common form of arthritis and cause of joint pain in adults. It affects more than 500 million people worldwide. Patients develop osteoarthritis when the structure of the protective cartilage that covers the bones begins to deteriorate. Recent research shows that multiple drugs in development are promising to treat osteoarthritis. Yet, most physicians agree that we still do not have enough effective treatments for this condition. What works for one person might not work for someone else. Consequently, osteoarthritis research is very important because understanding what causes osteoarthritis or why it progresses remains controversial. In fact, although articular cartilage is the primary target of the disease, both subchondral bone and synovium are often actively involved. This book describes the details of both surgical and non-surgical treatment options for osteoarthritis.
The last decade has ushered in an exciting new era in the pathophysiology and treatment of atopic dermatitis (AD). In this book, we shed light on the latest breakthroughs in systemic treatments for moderate-to-severe AD. In particular, we focus on the role and indication of JAK inhibitors, the role of natural killer cells in opening doors to new therapies, newly validated treatments, disease-based community data of current treatments, and the most recent clinical efficacy data of novel agents that have revolutionized the management of moderate-to-severe AD.
In the dynamic world of cellular biology, the intricate dance of life and death plays out through the lens of cytotoxicity. Delve deep into cellular responses’ mysteries, where threats and defenses wage a microscopic war, influencing the broader landscape of health and disease. This authoritative volume on cytotoxicity encapsulates the breadth and depth of current knowledge, illuminating pathways that have been meticulously charted and those yet to be discovered. Each chapter, penned by experts in the field, unveils the molecular intricacies, external triggers, and translational potential of understanding cellular damage. Key Highlights: •Comprehensive explorations of molecular mechanism...
The 4th International Conference on Modern Education and Information Management (ICMEIM 2023) was successfully held from September 8th to 10th, 2023 in Wuhan, China. This conference aimed to bring together scholars, researchers, and practitioners from around the world to discuss and exchange ideas on the latest trends and advancements in modern education and information management. The conference program featured a diverse range of research topics, including educational technology, digital learning, information systems, and knowledge management. With a focus on exploring innovative approaches and strategies, the conference provided a platform for participants to present their research findin...
This book uses facts and data to prove that socialist public sectors are still in a predominant position in China. Based on previous research and studies, a set of methods for measuring the structure of public or non-public owned economy is offered in this book. As is remarked by the authors, China’s basic economic system, namely the system with the public sector remaining dominant and diverse sectors of the economy developing side by side, represents an efficient approach towards mutual benefit, common prosperity and peaceful co-existence.
"Tangled Titans offers the most current and comprehensive assessment available of United States-China relations. In this definitive book, leading experts consider the past, present, and future of this complex relationship through an in-depth exploration of its historical, domestic, bilateral, regional, and global contexts. Never in modern history have two great powers been so deeply intertwined, yet so suspicious and potentially antagonistic. Readers will find Tangled Titans essential reading to understand the current dynamics and future direction of relations between the world's two most important powers."--Page 4 of cover.
The Ming dynasty becomes a battleground for the Brotherhood of Assassins and the Order of the Templars in this novel from a previously unexplored part of the beloved 'Assassin's Creed' universe.